Lalioside

Lalioside

SCHEMBL21130709

CC(=O)c1c(O)cc(O)c(O)c1O[C@H]1O[C@@H](CO)[C@H](O)[C@@H](O)[C@@H]1O

nearest known ligand 0.69

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC28A3 Q9HAS3 5/20 0.69
MEN1 O00255 2/20 0.53
KMT2A Q03164 2/20 0.53
KDM4E B2RXH2 2/20 0.53
CYP3A4 P08684 2/20 0.53
MAPT P10636 2/20 0.53
ALDH1A1 P00352 1/20 0.53
MAPK1 P28482 1/20 0.53
RECQL P46063 1/20 0.53
TDP1 Q9NUW8 1/20 0.53
DYRK1A Q13627 1/20 0.53
CA12 O43570 1/20 0.51
CA1 P00915 1/20 0.51
CA7 P43166 1/20 0.51
CA9 Q16790 1/20 0.51
CA13 Q8N1Q1 1/20 0.51
PTPN1 P18031 1/20 0.49
SOST Q9BQB4 1/20 0.49
POLB P06746 1/20 0.49
SLC5A1 P13866 3/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Lalioside SCHEMBL29350257 1.00 SLC28A3 (0.69) SLC28A3MEN1KMT2AKDM4ECYP3A4
SCHEMBL31677394 0.84 SLC28A3 (0.77) SLC28A3KDM4EMAPTMAPK1DYRK1A
SCHEMBL29083298 0.81 SLC28A3 (1.00) SLC28A3KDM4ECYP3A4MAPTDYRK1A
SCHEMBL21130707 0.81 SLC28A3 (1.00) SLC28A3KDM4ECYP3A4MAPTDYRK1A
SCHEMBL29353844 0.81 SLC28A3 (1.00) SLC28A3KDM4ECYP3A4MAPTDYRK1A
SCHEMBL5191128 0.78 SLC28A3 (0.55) SLC28A3MEN1KMT2ACA12CA1
SCHEMBL5181431 0.77 USP2 (0.58) SLC28A3MEN1KMT2AKDM4ECYP3A4
SCHEMBL13577089 0.77 USP2 (0.58) SLC28A3MEN1KMT2AKDM4ECYP3A4
SCHEMBL3140292 0.77 USP2 (0.58) SLC28A3MEN1KMT2AKDM4ECYP3A4
SCHEMBL5181145 0.77 USP2 (0.58) SLC28A3MEN1KMT2AKDM4ECYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220204776-A1 PROCESS FOR PREPARING A LAWSONIA INERMIS EXTRACT PIERRE FABRE DERMO-COSMETIQUE (FR) 2022-06-30 US disclosed
US-11207265-B2 Extract of the aerial parts of Lawsonia inermis and its preparation method PIERRE FABRE DERMO-COSME FIQUE (FR) 2021-12-28 US disclosed
WO-2020249746-A1 PROCESS FOR PREPARING A LAWSONIA INERMIS EXTRACT PIERRE FABRE DERMO-COSMETIQUE (FR) 2020-12-17 WO disclosed
US-20200330365-A1 EXTRACT OF THE AERIAL PARTS OF LAWSONIA INERMIS AND ITS PREPARATION METHOD PIERRE FABRE DERMO-COSMETIQUE (FR) 2020-10-22 US disclosed
WO-2019115651-A1 EXTRACT OF THE AERIAL PARTS OF LAWSONIA INERMIS AND ITS PREPARATION METHOD PIERRE FABRE DERMO-COSMETIQUE (FR) 2019-06-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220204776-A1 PROCESS FOR PREPARING A LAWSONIA INERMIS EXTRACT KRT18, LMNB1, CKMT1A; CKMT1B SLC28A3 4875/4885MEN1 3840/4885KMT2A 3803/4885
US-11207265-B2 Extract of the aerial parts of Lawsonia inermis and its preparation method KRT18, MKI67, CD68 SLC28A3 4874/4885MEN1 3539/4885KMT2A 2397/4885
US-20200330365-A1 EXTRACT OF THE AERIAL PARTS OF LAWSONIA INERMIS AND ITS PREPARATION METHOD KRT18, MKI67, CD68 SLC28A3 4874/4885MEN1 3539/4885KMT2A 2397/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.