Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30171 | 0.92 | THRB (0.40) | THRBLMNA | |
| SCHEMBL22654527 | 0.87 | THRB (0.44) | THRBLMNA | |
| SCHEMBL11004515 | 0.80 | THRB (0.35) | THRBLMNA | |
| SCHEMBL11606263 | 0.79 | DNM1 (0.41) | — | |
| SCHEMBL11290325 | 0.77 | — | — | |
| SCHEMBL1877496 | 0.76 | — | — | |
| SCHEMBL11004533 | 0.75 | THRB (0.35) | THRBLMNA | |
| SCHEMBL11719323 | 0.75 | MEN1 (0.35) | THRBLMNA | |
| Hydrogen Sulfide SCHEMBL27817780 | 0.74 | THRB (0.38) | THRBLMNA | |
| SCHEMBL3802704 | 0.73 | OPRM1 (0.42) | THRBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10336717-B2 | Inhibitors of beta-secretase | VITAE PHARMACEUTICALS, LLC (US) | 2019-07-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10336717-B2 | Inhibitors of beta-secretase | BACE1, BACE2, PSEN1 | THRB 2578/4885LMNA 521/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.