Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5599840 | 0.81 | MEN1 (0.66) | GBA1ALDH1A1TSHRLMNAHPGD | |
| SCHEMBL12406336 | 0.80 | GBA1 (0.66) | GBA1ALDH1A1TSHRKMT2AMEN1 | |
| SCHEMBL19011400 | 0.80 | GBA1 (0.61) | GBA1ALDH1A1TSHRKMT2AMEN1 | |
| SCHEMBL13840405 | 0.80 | GBA1 (0.61) | GBA1ALDH1A1TSHRKMT2AMEN1 | |
| SCHEMBL10332261 | 0.78 | GBA1 (0.59) | GBA1ALDH1A1TSHRLMNAHPGD | |
| SCHEMBL28686588 | 0.77 | GBA1 (0.67) | GBA1ALDH1A1TSHRKMT2AMEN1 | |
| SCHEMBL9485564 | 0.77 | ALDH1A1 (0.65) | GBA1ALDH1A1TSHRKMT2AMEN1 | |
| SCHEMBL4463262 | 0.76 | GBA1 (0.70) | GBA1ALDH1A1TSHRKMT2AMEN1 | |
| SCHEMBL3716602 | 0.76 | GBA1 (0.70) | GBA1ALDH1A1TSHRKMT2AMEN1 | |
| SCHEMBL3723855 | 0.76 | GBA1 (0.70) | GBA1ALDH1A1TSHRKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10548862-B2 | Topical formulation and method for preventing or treating acne | Wu, Lester J. (US) | 2020-02-04 | — | — | US | disclosed |
| US-20190201356-A1 | TOPICAL FORMULATION AND METHOD FOR PREVENTING OR TREATING ACNE | GONGWIN BIOPHARM CO., LTD. (TW) | 2019-07-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10548862-B2 | Topical formulation and method for preventing or treating acne | CUTA, STS, ALAD | GBA1 1583/4885ALDH1A1 669/4885TSHR 2402/4885 |
| US-20190201356-A1 | TOPICAL FORMULATION AND METHOD FOR PREVENTING OR TREATING ACNE | CUTA, STS, ALAD | GBA1 1583/4885ALDH1A1 669/4885TSHR 2402/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.