Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 1/20 | 0.56 |
| ▸ | TYMP | P19971 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | ALB | P02768 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.48 |
| ▸ | IMPDH2 | P12268 | 4/20 | 0.47 |
| ▸ | IMPDH1 | P20839 | 2/20 | 0.45 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.45 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20282682 | 0.89 | TYMP (0.68) | P2RX3TYMPALDH1A1LMNAALB | |
| SCHEMBL21417135 | 0.89 | TYMP (0.68) | P2RX3TYMPALDH1A1LMNAALB | |
| SCHEMBL21133316 | 0.86 | P2RX3 (0.56) | P2RX3TYMPALDH1A1LMNAALB | |
| SCHEMBL21133338 | 0.86 | P2RX3 (0.56) | P2RX3TYMPALDH1A1LMNAALB | |
| SCHEMBL20324606 | 0.85 | POLB (0.67) | POLBIMPDH2IMPDH1TAS1R3TAS1R1 | |
| SCHEMBL9856344 | 0.85 | POLB (0.67) | POLBIMPDH2IMPDH1TAS1R3TAS1R1 | |
| SCHEMBL21132941 | 0.85 | POLB (0.67) | POLBIMPDH2IMPDH1TAS1R3TAS1R1 | |
| SCHEMBL9153227 | 0.85 | LMNA (0.64) | P2RX3TYMPALDH1A1LMNAALB | |
| SCHEMBL21133329 | 0.84 | TYMP (0.46) | P2RX3TYMPALDH1A1LMNAALB | |
| SCHEMBL8616900 | 0.83 | P2RY1 (0.66) | POLBP2RY1TAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3505527-A1 | CYCLIC DINUCLEOTIDES FOR CYTOKINE INDUCTION | Invivogen (FR) | 2019-07-03 | — | — | EP | disclosed |