Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 1/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ALB | P02768 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | IMPDH2 | P12268 | 6/20 | 0.47 |
| ▸ | TYMP | P19971 | 2/20 | 0.46 |
| ▸ | IMPDH1 | P20839 | 2/20 | 0.45 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.45 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.45 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.45 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.45 |
| ▸ | LDHA | P00338 | 1/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.45 |
| ▸ | FBP1 | P09467 | 1/20 | 0.45 |
| ▸ | SRC | P12931 | 1/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.45 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.45 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21133316 | 1.00 | P2RX3 (0.56) | P2RX3ADORA3ALDH1A1LMNAALB | |
| SCHEMBL21133326 | 0.92 | P2RX3 (0.55) | P2RX3ADORA3ALDH1A1LMNAALB | |
| SCHEMBL21133320 | 0.88 | P2RX3 (0.56) | P2RX3 | |
| SCHEMBL21132767 | 0.86 | P2RX3 (0.56) | P2RX3ADORA3ALDH1A1LMNAALB | |
| SCHEMBL21637000 | 0.86 | P2RX3 (0.49) | P2RX3ADORA3ALDH1A1LMNAALB | |
| SCHEMBL21417496 | 0.85 | NT5E (0.56) | IMPDH2IMPDH1STING1P2RY2TAS1R3 | |
| SCHEMBL21636981 | 0.85 | NT5E (0.56) | IMPDH2IMPDH1STING1P2RY2TAS1R3 | |
| SCHEMBL21636997 | 0.85 | NT5E (0.56) | IMPDH2IMPDH1STING1P2RY2TAS1R3 | |
| SCHEMBL9850102 | 0.85 | ALDH1A1 (0.64) | P2RX3ADORA3ALDH1A1LMNAALB | |
| SCHEMBL21637077 | 0.84 | P2RX3 (0.42) | P2RX3ADORA3ALDH1A1LMNAALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020016782-A1 | CYCLIC DINUCLEOTIDES AS STING AGONISTS | JANSSEN BIOTECH, INC. (US) | 2020-01-23 | — | — | WO | disclosed |
| EP-3505527-A1 | CYCLIC DINUCLEOTIDES FOR CYTOKINE INDUCTION | Invivogen (FR) | 2019-07-03 | — | — | EP | disclosed |