Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19987937 | 0.83 | NOS2 (0.40) | TSHRTHRB | |
| SCHEMBL21133101 | 0.82 | TSHR (0.39) | TSHRALDH1A1 | |
| SCHEMBL9321905 | 0.78 | THRB (0.55) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL20537360 | 0.78 | TSHR (0.49) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL11520523 | 0.78 | TSHR (0.49) | TSHRTHRBPOLBAPEX1HTT | |
| Acetic Acid SCHEMBL11303299 | 0.77 | TSHR (0.47) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL7892697 | 0.77 | TSHR (0.66) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL4650020 | 0.77 | TSHR (0.50) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL13950019 | 0.77 | THRB (0.53) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL2047037 | 0.76 | TSHR (0.39) | TSHRTHRBPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3299400-B1 | LATEX FUNCTIONALIZED WITH STRUCTURAL UNITS OF AN AMINO ACID | ROHM & HAAS (US) | 2019-06-26 | — | — | EP | disclosed |