Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 20/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18489989 | 1.00 | CYP11B2 (0.69) | CYP11B2 | |
| SCHEMBL20402785 | 0.84 | CYP11B2 (0.70) | CYP11B2 | |
| SCHEMBL17207634 | 0.83 | CYP11B2 (0.68) | CYP11B2 | |
| SCHEMBL18502910 | 0.79 | CYP11B2 (0.68) | CYP11B2 | |
| SCHEMBL18489986 | 0.78 | CYP11B2 (0.51) | CYP11B2 | |
| SCHEMBL28544147 | 0.78 | CYP11B2 (0.51) | CYP11B2 | |
| SCHEMBL18502833 | 0.74 | CYP11B2 (0.76) | CYP11B2 | |
| SCHEMBL17207558 | 0.72 | CYP11B2 (0.75) | CYP11B2 | |
| SCHEMBL17207654 | 0.70 | CYP11B2 (1.00) | CYP11B2 | |
| SCHEMBL18790696 | 0.70 | CYP11B2 (0.61) | CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106232587-B | Disubstituted 1,2, 4-triazine compounds | 田边三菱制药株式会社 | 2021-04-13 | — | — | CN | disclosed |
| US-10329263-B2 | Disubstituted 1, 2, 4-triazine compound | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2019-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10329263-B2 | Disubstituted 1, 2, 4-triazine compound | NR3C2, REN, NR5A1 | CYP11B2 19/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.