Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 16/20 | 0.51 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | TYK2 | P29597 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18489986 | 1.00 | CYP11B2 (0.51) | CYP11B2JAK2JAK1TYK2JAK3 | |
| SCHEMBL21133412 | 0.78 | CYP11B2 (0.69) | CYP11B2 | |
| SCHEMBL18489989 | 0.78 | CYP11B2 (0.69) | CYP11B2 | |
| SCHEMBL17207634 | 0.77 | CYP11B2 (0.68) | CYP11B2 | |
| SCHEMBL18502910 | 0.73 | CYP11B2 (0.68) | CYP11B2 | |
| SCHEMBL20514060 | 0.71 | PIM2 (0.42) | CYP11B2 | |
| SCHEMBL17207706 | 0.64 | ALDH1A1 (0.57) | CYP11B2AR | |
| SCHEMBL15345120 | 0.63 | TRPA1 (0.47) | CYP11B2AR | |
| SCHEMBL18502909 | 0.62 | TRPA1 (0.41) | CYP11B2AR | |
| SCHEMBL20402785 | 0.62 | CYP11B2 (0.70) | CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106232587-B | Disubstituted 1,2, 4-triazine compounds | 田边三菱制药株式会社 | 2021-04-13 | — | — | CN | disclosed |