SCHEMBL21133565

SCHEMBL21133565

[N-]=[N+]=NCc1cc(C[C@H](N)C(O)O)cs1

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ KAT2B Q92831 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15469228 0.82 SLC7A5 (0.41) —
SCHEMBL22652851 0.71 LTB4R (0.44) KAT2B
SCHEMBL21465906 0.69 — —
SCHEMBL13981489 0.67 KAT2B (0.34) KAT2B
SCHEMBL16137216 0.60 ALDH1A1 (0.33) —
SCHEMBL17593853 0.59 — —
SCHEMBL13927495 0.58 CSNK1E (0.48) —
SCHEMBL13623245 0.58 KAT2B (0.34) KAT2B
SCHEMBL14084678 0.57 HDAC3 (0.34) —
SCHEMBL22431194 0.56 EPHX1 (0.58) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3505534-A1 ANTIBODIES COMPRISING SITESPECIFIC NONNATURAL AMINO ACID RESIDUES, METHODS OF THEIR PREPARATION AND METHODS OF THEIR USE Sutro Biopharma, Inc. (US) 2019-07-03 — — EP disclosed
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