Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 4/20 | 0.44 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.34 |
| ▸ | DAO | P14920 | 2/20 | 0.33 |
| ▸ | PTPRB | P23467 | 1/20 | 0.31 |
| ▸ | CDC25A | P30304 | 1/20 | 0.31 |
| ▸ | CDC25B | P30305 | 1/20 | 0.31 |
| ▸ | PTEN | P60484 | 1/20 | 0.31 |
| ▸ | PTPMT1 | Q8WUK0 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15469228 | 0.76 | SLC7A5 (0.41) | — | |
| SCHEMBL15521418 | 0.74 | FFAR1 (0.53) | KEAP1FFAR1HDAC3HDAC1HDAC2 | |
| SCHEMBL16644962 | 0.71 | HDAC1 (0.42) | HDAC1HDAC6 | |
| SCHEMBL21133565 | 0.71 | KAT2B (0.31) | KAT2B | |
| SCHEMBL20751484 | 0.70 | HDAC6 (0.39) | HDAC1HDAC6 | |
| SCHEMBL16644964 | 0.70 | HDAC6 (0.37) | KAT2BFFAR1HDAC6 | |
| SCHEMBL4675508 | 0.68 | LTB4R (0.50) | LTB4RKEAP1FFAR1DAONPSR1 | |
| SCHEMBL28882561 | 0.68 | LTB4R (0.47) | LTB4RKEAP1FFAR1DAONPSR1 | |
| SCHEMBL25240683 | 0.67 | DAO (0.47) | LTB4RKEAP1FFAR1DAONPSR1 | |
| SCHEMBL16644961 | 0.67 | PPARA (0.46) | KAT2BNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020227105-A1 | ANTI-BCMA ANTIBODY CONJUGATES | SUTRO BIOPHARMA, INC. (US) | 2020-11-12 | — | — | WO | disclosed |