Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 6/20 | 0.49 |
| ▸ | CA2 | P00918 | 6/20 | 0.49 |
| ▸ | CA9 | Q16790 | 6/20 | 0.49 |
| ▸ | CA12 | O43570 | 5/20 | 0.49 |
| ▸ | PRKCA | P17252 | 1/20 | 0.46 |
| ▸ | AKT1 | P31749 | 1/20 | 0.46 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.44 |
| ▸ | FYN | P06241 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16392573 | 0.87 | CA1 (0.49) | LMNAKMT2APOLBALDH1A1CA1 | |
| SCHEMBL9524271 | 0.87 | CA1 (0.49) | LMNAKMT2APOLBALDH1A1CA1 | |
| SCHEMBL9735191 | 0.87 | CA1 (0.49) | LMNAKMT2APOLBALDH1A1CA1 | |
| SCHEMBL16392618 | 0.87 | LMNA (0.50) | LMNAKMT2APOLBALDH1A1CA1 | |
| SCHEMBL16392904 | 0.87 | LMNA (0.51) | LMNAKMT2APOLBALDH1A1CA1 | |
| SCHEMBL24997325 | 0.85 | LMNA (0.48) | LMNAKMT2APOLBALDH1A1CA1 | |
| SCHEMBL22559700 | 0.84 | LMNA (0.55) | LMNAKMT2APOLBALDH1A1CA1 | |
| SCHEMBL21138671 | 0.83 | LMNA (0.65) | LMNAKMT2APOLBALDH1A1CA1 | |
| SCHEMBL21058368 | 0.83 | LMNA (0.65) | LMNAKMT2APOLBALDH1A1CA1 | |
| SCHEMBL21137853 | 0.83 | LMNA (0.51) | LMNAKMT2APOLBALDH1A1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190194655-A1 | POLYNUCLEOTIDE CONSTRUCTS HAVING AN AUXILIARY MOIETY NON-BIOREVERSIBLY LINKED TO AN INTERNUCLEOSIDE PHOSPHATE OR PHOSPHOROTHIOATE | BRADSHAW CURT W (US) | 2019-06-27 | — | — | US | disclosed |