SCHEMBL2113438

SCHEMBL2113438

Cc1nc2nc(NOCCO)[nH]c(=O)c2[nH]1

nearest known ligand 0.45

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
GDA Q9Y2T3 1/20 0.35
FGFR1 P11362 5/20 0.34
FGFR2 P21802 5/20 0.34
FGFR3 P22607 2/20 0.34
XDH P47989 3/20 0.33
PNP P00491 1/20 0.32
NUDT1 P36639 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5133744 0.87 XDH (0.39) GDAFGFR1FGFR2FGFR3XDH
SCHEMBL9275474 0.84 XDH (0.38) GDAFGFR1FGFR2FGFR3XDH
SCHEMBL3512356 0.80 GDA (0.35) GDAFGFR1FGFR2FGFR3XDH
SCHEMBL65614 0.74 GDA (0.40) GDAFGFR1FGFR2FGFR3XDH
SCHEMBL8591402 0.73 FGFR1 (0.51) GDAFGFR1FGFR2FGFR3PNP
SCHEMBL16513137 0.72 GDA (0.64) GDAFGFR1FGFR2FGFR3
SCHEMBL26155922 0.71 PNP (0.48) PNPNUDT1
SCHEMBL6270959 0.69 FYN (0.52)
SCHEMBL27503507 0.69 XDH (0.62) GDAXDH
SCHEMBL4384740 0.68 XDH (0.67) XDHPNP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8679454-B2 Particle immobilized coatings and uses thereof SURMODICS, INC. (US) 2014-03-25 US disclosed
US-8158106-B2 Drug delivery; microparticles immobilized on polymer surface SURMODICS, INC. (US) 2012-04-17 US disclosed
US-20090186070-A1 Particle immobilized coating and uses thereof Surmodics Coatings, LLC 2009-07-23 US disclosed
EP-1434571-B1 PARTICLE IMMOBILIZED COATINGS AND USES THEREOF SURMODICS INC (US) 2005-05-11 EP disclosed
EP-1478403-A1 RESPONSIVE MICROGEL AND METHODS RELATED THERETO SUPRATEK PHARMA, INC. (CA) 2004-11-24 EP disclosed
US-RE38341-E1 Method for electrokinetic delivery of medicaments BIOPHORETIC THERAPEUTIC SYSTEMS, LLC 2003-12-09 US disclosed
WO-2003063909-A1 RESPONSIVE MICROGEL AND METHODS RELATED THERETO SUPRATEK PHARMA INC. (US) 2003-08-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090186070-A1 Particle immobilized coating and uses thereof SELP, SELPLG, PLAUR GDA 2894/4885FGFR1 2010/4885FGFR2 2094/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.