Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 3/20 | 0.38 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.34 |
| ▸ | FGFR2 | P21802 | 3/20 | 0.34 |
| ▸ | PNP | P00491 | 3/20 | 0.34 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.33 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.33 |
| ▸ | POLA1 | P09884 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5133744 | 0.88 | XDH (0.39) | XDHGDAFGFR1FGFR2PNP | |
| SCHEMBL2113438 | 0.84 | GDA (0.35) | XDHGDAFGFR1FGFR2PNP | |
| SCHEMBL27775482 | 0.79 | XDH (0.61) | XDHGDAPOLA1 | |
| SCHEMBL3512356 | 0.77 | GDA (0.35) | XDHGDAFGFR1FGFR2PNP | |
| SCHEMBL65614 | 0.77 | GDA (0.40) | XDHGDAFGFR1FGFR2PNP | |
| SCHEMBL26155922 | 0.74 | PNP (0.48) | PNPNUDT1 | |
| SCHEMBL4384740 | 0.74 | XDH (0.67) | XDHPNPPOLA1 | |
| SCHEMBL8591402 | 0.73 | FGFR1 (0.51) | GDAFGFR1FGFR2PNPFGFR3 | |
| SCHEMBL16513137 | 0.72 | GDA (0.64) | GDAFGFR1FGFR2FGFR3 | |
| SCHEMBL6270959 | 0.72 | FYN (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0662819-A1 | AN ANTIVIRALLY ACTIVE PHARMACEUTICAL OIL-IN-WATER EMULSION CONTAINING 9- (2-HYDROXYETHOXY)METHYL]GUANINE (ACYCLOVIR) OR A SALT OR ESTER THEREOF. | GEA FARMACEUTISK FABRIK AS (DK) | 1995-07-19 | — | — | EP | claimed |
| WO-1994005258-A1 | AN ANTIVIRALLY ACTIVE PHARMACEUTICAL OIL-IN-WATER EMULSION CONTAINING 9-[(2-HYDROXYETHOXY)METHYL]GUANINE (ACYCLOVIR) OR A SALT OR ESTER THEREOF | A/S GEA FARMACEUTISK FABRIK (DK) | 1994-03-17 | — | — | WO | claimed |