Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ACP1 | P24666 | 2/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 6/20 | 0.38 |
| ▸ | GBA1 | P04062 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19162532 | 0.98 | TSHR (0.39) | TSHRMAPK1HSD17B10ACP1ABCG2 | |
| SCHEMBL19161925 | 0.94 | TSHR (0.35) | TSHRMAPK1HSD17B10ACP1ABCG2 | |
| SCHEMBL19162724 | 0.93 | ROCK2 (0.35) | TSHRMAPK1HSD17B10ACP1ABCG2 | |
| SCHEMBL19161690 | 0.93 | TSHR (0.34) | TSHRMAPK1HSD17B10ACP1ABCG2 | |
| SCHEMBL19163344 | 0.93 | ROCK2 (0.35) | TSHRMAPK1HSD17B10ACP1ABCG2 | |
| SCHEMBL19162967 | 0.93 | TSHR (0.39) | TSHRMAPK1HSD17B10ACP1ABCG2 | |
| SCHEMBL19163011 | 0.91 | TSHR (0.38) | TSHRMAPK1HSD17B10ACP1ABCG2 | |
| SCHEMBL19163341 | 0.91 | FLT3 (0.33) | TSHRMAPK1HSD17B10ABCG2LMNA | |
| SCHEMBL19163336 | 0.90 | ABCB1 (0.31) | TSHRMAPK1HSD17B10 | |
| SCHEMBL19162341 | 0.90 | TSHR (0.40) | TSHRMAPK1HSD17B10ACP1ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10347845-B2 | Nitrogen-containing condensed cyclic compound and organic light emitting device using same | LG CHEM, LTD. (KR) | 2019-07-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10347845-B2 | Nitrogen-containing condensed cyclic compound and organic light emitting device using same | CRY1, NOS1, NOLC1 | TSHR 4646/4885MAPK1 676/4885HSD17B10 2894/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.