Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5206969 | 0.86 | — | — | |
| SCHEMBL1145229 | 0.86 | — | — | |
| SCHEMBL20078087 | 0.85 | — | — | |
| SCHEMBL12424643 | 0.75 | SHBG (0.33) | SHBG | |
| SCHEMBL1145165 | 0.75 | — | — | |
| SCHEMBL21917830 | 0.74 | — | — | |
| SCHEMBL87744 | 0.72 | — | — | |
| SCHEMBL7732642 | 0.72 | CYP1A2 (0.40) | SHBGTSHR | |
| SCHEMBL1145618 | 0.72 | CYP1A2 (0.40) | SHBGTSHR | |
| SCHEMBL7737936 | 0.72 | CYP1A2 (0.40) | SHBGTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10323000-B2 | Indole derivatives and their use in neurodegenerative diseases | MERCK PATENT GMBH (DE) | 2019-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10323000-B2 | Indole derivatives and their use in neurodegenerative diseases | P2RX3, ADORA2A, P2RX7 | SHBG 4656/4885TSHR 2385/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.