Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G10 | O15496 | 3/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.40 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MME | P08473 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11892766 | 0.84 | LMNA (0.53) | CYP2C9LMNAPOLBTAS1R3TAS1R1 | |
| SCHEMBL16329867 | 0.80 | TAS1R3 (0.44) | PLA2G10LMNATAS1R3TAS1R1BIRC2 | |
| SCHEMBL5208258 | 0.78 | TAS1R3 (0.40) | PLA2G10PSMB5LMNATAS1R3TAS1R1 | |
| SCHEMBL13662686 | 0.77 | CYP2C9 (0.46) | CYP2C9LMNAPOLBMEN1KMT2A | |
| SCHEMBL17776983 | 0.77 | CYP2C9 (0.46) | CYP2C9LMNAPOLBMEN1KMT2A | |
| SCHEMBL24741521 | 0.77 | CYP2C9 (0.46) | PLA2G10CYP2C9PSMB5LMNAMEN1 | |
| SCHEMBL20054250 | 0.77 | CYP2C9 (0.46) | PLA2G10CYP2C9PSMB5LMNAMEN1 | |
| SCHEMBL20438368 | 0.77 | PLA2G10 (0.44) | PLA2G10PSMB5LMNAMEN1KMT2A | |
| SCHEMBL12583518 | 0.76 | DNM1 (0.48) | CYP2C9LMNAPOLBTAS1R3TAS1R1 | |
| SCHEMBL12583514 | 0.76 | DNM1 (0.48) | CYP2C9LMNAPOLBTAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10342846-B2 | Nanoparticle drug delivery systems | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2019-07-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10342846-B2 | Nanoparticle drug delivery systems | EGFR, EPHA6, LPAR6 | PLA2G10 1430/4885CYP2C9 1101/4885PSMB5 2879/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.