SCHEMBL21134688

SCHEMBL21134688

CC(=C\c1cc(C)cc(C)c1)/C(=N/N)NN

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.33
MAPT P10636 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29407659 0.68 SLC9A3 (0.40) GAAMAPT
SCHEMBL16140271 0.68 ALDH1A1 (0.39)
SCHEMBL28489139 0.66 MAPT (0.45) MAPT
SCHEMBL27892880 0.62 ALDH1A1 (0.33)
SCHEMBL16141472 0.62 AKR1C3 (0.57)
SCHEMBL28235567 0.59 ALDH1A1 (0.54) MAPT
SCHEMBL21056103 0.58 GABRA1 (0.49) GAAMAPT
SCHEMBL21134491 0.58 GABRA1 (0.49) GAAMAPT
SCHEMBL21056104 0.58 GABRA1 (0.49) GAAMAPT
Hydroxyamine SCHEMBL16975254 0.56 ALDH1A1 (0.64) GAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3498273-A1 PHARMACEUTICAL COMPOSITION FOR MODULATING THE RESPONSE OF A GABA-A RECEPTOR Universität Wien (AT) 2019-06-19 EP disclosed