Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIKFYVE | Q9Y2I7 | 5/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 6/20 | 0.33 |
| ▸ | KDM5A | P29375 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 4/20 | 0.33 |
| ▸ | MTOR | P42345 | 4/20 | 0.33 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23272141 | 0.85 | PIKFYVE (0.64) | PIKFYVEGAAPOLBMAPTKDM4E | |
| SCHEMBL30312382 | 0.85 | PIKFYVE (0.64) | PIKFYVEGAAPOLBMAPTKDM4E | |
| SCHEMBL21135830 | 0.82 | JAK3 (0.41) | PIKFYVEPIK3CAKDM5APIK3CBMTOR | |
| SCHEMBL21135838 | 0.79 | TRPM8 (0.42) | PIKFYVEGAAMAPTMEN1MAPK1 | |
| SCHEMBL21135798 | 0.77 | PIK3CA (0.41) | PIK3CAPIK3CDPIK3CBMTORPIK3R1 | |
| SCHEMBL21135844 | 0.77 | PIK3CA (0.42) | PIKFYVEGAAPOLBMAPTMEN1 | |
| SCHEMBL21135799 | 0.74 | PIK3CA (0.42) | MAPK1LMNAPIK3CAPIK3CDPIK3CB | |
| SCHEMBL21135831 | 0.72 | PIK3CA (0.42) | PIKFYVEPIK3CAPIK3CDPIK3CBMTOR | |
| SCHEMBL21135797 | 0.72 | PIK3CD (0.39) | PIKFYVEPIK3CAPIK3CDPIK3CBMTOR | |
| SCHEMBL21054603 | 0.70 | PIKFYVE (0.55) | PIKFYVEGAAPOLBMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019113523-A1 | COMPOUNDS AND THERAPEUTIC USES THEREOF | BAJJI ASHOK (US) | 2019-06-13 | — | — | WO | disclosed |