Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 8/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 7/20 | 0.42 |
| ▸ | PIK3R1 | P27986 | 6/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.39 |
| ▸ | STAT3 | P40763 | 3/20 | 0.37 |
| ▸ | SETD2 | Q9BYW2 | 1/20 | 0.37 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.36 |
| ▸ | PIKFYVE | Q9Y2I7 | 2/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30312433 | 0.81 | PIKFYVE (0.61) | MTORPIK3CAPIKFYVEPIK3CBKDM4E | |
| SCHEMBL21054891 | 0.81 | PIKFYVE (0.61) | MTORPIK3CAPIKFYVEPIK3CBKDM4E | |
| SCHEMBL21135486 | 0.75 | PIK3CD (0.41) | MTORPIK3CAPIK3R1NPY5RSTAT3 | |
| SCHEMBL21135783 | 0.75 | PIK3CD (0.46) | MTORPIK3CAPIK3R1NPY5RSTAT3 | |
| SCHEMBL21135407 | 0.75 | PIK3CD (0.44) | MTORPIK3CAPIK3R1NPY5RSTAT3 | |
| SCHEMBL21135404 | 0.75 | PIK3R1 (0.51) | MTORPIK3CAPIK3R1NPY5RSTAT3 | |
| SCHEMBL21135300 | 0.75 | PIKFYVE (0.44) | MTORPIK3CAPIK3R1NPY5RSTAT3 | |
| SCHEMBL21135293 | 0.74 | MAPT (0.46) | MTORPIK3CAPIK3R1STAT3SETD2 | |
| SCHEMBL21135409 | 0.74 | PIK3CD (0.47) | NPY5RSTAT3SETD2ALDH1A1LMNA | |
| SCHEMBL21135499 | 0.73 | FLT3 (0.41) | MTORPIK3CAPIK3R1NPY5RSTAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019113523-A1 | COMPOUNDS AND THERAPEUTIC USES THEREOF | BAJJI ASHOK (US) | 2019-06-13 | — | — | WO | disclosed |