SCHEMBL21136043

SCHEMBL21136043

CS(=O)(=O)C(F)(CC12CC3CC(CC(C3)C1)C2)S(=O)(=O)O

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.35
SCN9A Q15858 3/20 0.34
EPHX1 P07099 1/20 0.33
HSD17B10 Q99714 1/20 0.33
EPHX2 P34913 7/20 0.33
TSHR P16473 1/20 0.33
SCN5A Q14524 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21136970 0.83 SMN1; SMN2 (0.34) ALDH1A1SCN9AEPHX1HSD17B10EPHX2
SCHEMBL3790410 0.79 ALDH1A1 (0.36) ALDH1A1EPHX1HSD17B10EPHX2TSHR
SCHEMBL26190781 0.79 SCN9A (0.36) ALDH1A1SCN9AHSD17B10TSHR
SCHEMBL3785565 0.77 ALDH1A1 (0.35) ALDH1A1EPHX1HSD17B10EPHX2TSHR
SCHEMBL21136976 0.77 EPHX1 (0.33) SCN9AEPHX1SCN5A
SCHEMBL21135952 0.77 ALDH1A1 (0.35) ALDH1A1HSD17B10EPHX2TSHR
SCHEMBL21135752 0.76 BPTF (0.38) ALDH1A1SCN9AEPHX1SCN5A
SCHEMBL21135981 0.75 ALDH1A1 (0.38) ALDH1A1SCN9AHSD17B10EPHX2TSHR
SCHEMBL21135989 0.73 ALDH1A1 (0.36) ALDH1A1SCN9AHSD17B10EPHX2TSHR
SCHEMBL21136386 0.72 NPSR1 (0.38) ALDH1A1SCN9AHSD17B10EPHX2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190196326-A1 ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION, RESIST FILM, PATTERN FORMING METHOD, AND METHOD OF MANUFACTURING ELECTRONIC DEVICE FUJIFILM CORPORATION (JP) 2019-06-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190196326-A1 ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION, RESIST FILM, PATTERN FORMING METHOD, AND METHOD OF MANUFACTURING ELECTRONIC DEVICE RER1, ACTR5, RAD51 ALDH1A1 1556/4885SCN9A 2257/4885EPHX1 139/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.