Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.52 |
| ▸ | FPR1 | P21462 | 3/20 | 0.49 |
| ▸ | FPR2 | P25090 | 3/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 4/20 | 0.47 |
| ▸ | PTGES | O14684 | 2/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.46 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10178052 | 0.85 | NOTUM (0.49) | NOTUMFPR1FPR2TRPA1HRH4 | |
| SCHEMBL26970085 | 0.83 | NOTUM (0.58) | NOTUMTRPA1KDM2BCA12CA2 | |
| SCHEMBL21135466 | 0.83 | CYP3A4 (0.56) | NOTUMTRPA1CYP3A4CYP2C19 | |
| SCHEMBL7146014 | 0.83 | CYP3A4 (0.56) | NOTUMTRPA1CYP3A4CYP2C19 | |
| SCHEMBL21135575 | 0.83 | CYP3A4 (0.56) | NOTUMTRPA1CYP3A4CYP2C19 | |
| SCHEMBL25855629 | 0.81 | ESR1 (0.45) | CYP3A4CYP2C19 | |
| SCHEMBL2166648 | 0.81 | HRH4 (0.56) | NOTUMPTGESHRH4HRH3CA12 | |
| SCHEMBL13346444 | 0.80 | TRPA1 (0.58) | NOTUMFPR1FPR2TRPA1KDM2B | |
| SCHEMBL21135458 | 0.80 | NOTUM (0.49) | NOTUMKCNH2MCHR1 | |
| SCHEMBL6271445 | 0.80 | NOTUM (0.49) | NOTUMKCNH2MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3371196-B1 | HETEROCYCLIC COMPOUNDS AS INHIBITORS OF PLATELET AGGREGATION | UNIV MONTREAL (CA) | 2021-10-27 | — | — | EP | disclosed |
| US-10329307-B2 | Heterocyclic compounds as inhibitors of platelet aggregation | UNIVERSITE DE MONTREAL (CA) | 2019-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10329307-B2 | Heterocyclic compounds as inhibitors of platelet aggregation | F12, F2, F3 | NOTUM 2703/4885FPR1 187/4885FPR2 624/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.