Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 6/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | SYK | P43405 | 2/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | TYMP | P19971 | 2/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KHK | P50053 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CDK8 | P49336 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7146014 | 0.85 | CYP3A4 (0.56) | CYP3A4MAP4K4SYKJAK2TYMP | |
| SCHEMBL21135496 | 0.85 | NOTUM (0.49) | CYP2D6MAP4K4SYKJAK2TYMP | |
| SCHEMBL77035 | 0.85 | KDM4E (0.49) | ESR2CYP3A4CYP2D6MAP4K4SYK | |
| SCHEMBL6271445 | 0.85 | NOTUM (0.49) | CYP2D6MAP4K4SYKJAK2TYMP | |
| SCHEMBL21135575 | 0.85 | CYP3A4 (0.56) | CYP3A4MAP4K4SYKJAK2TYMP | |
| SCHEMBL7790528 | 0.85 | EPHX2 (0.51) | CYP2D6MAP4K4SYKJAK2TYMP | |
| SCHEMBL21135458 | 0.85 | NOTUM (0.49) | CYP2D6MAP4K4SYKJAK2TYMP | |
| SCHEMBL21135466 | 0.85 | CYP3A4 (0.56) | CYP3A4MAP4K4SYKJAK2TYMP | |
| SCHEMBL21135739 | 0.85 | CYP2D6 (0.52) | CYP2D6MAP4K4TYMPPTPN1POLB | |
| SCHEMBL21135447 | 0.85 | CYP2D6 (0.52) | CYP2D6MAP4K4TYMPPTPN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230212158-A1 | SMALL MOLECULE INHIBITORS OF GALECTIN-3 | BRISTOL MYERS SQUIBB CO (US) | 2023-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230212158-A1 | SMALL MOLECULE INHIBITORS OF GALECTIN-3 | LGALS3, LGALS1, LGALS3BP | ESR1 4699/4885ESR2 3523/4885CYP3A4 4307/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.