Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.43 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.42 |
| ▸ | HTR3B | O95264 | 1/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.42 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL364796 | 0.86 | ADRA2A (0.45) | MEN1KMT2AADRA2AADRA1AHTR3E | |
| SCHEMBL11044403 | 0.84 | KDM4E (0.43) | MEN1KMT2AADRA2AADRA1AHTR3E | |
| SCHEMBL84489 | 0.82 | LPAR1 (0.50) | MEN1KMT2AHTR3EHTR3BHTR3A | |
| SCHEMBL20855437 | 0.80 | ADRA1A (0.49) | MEN1KMT2AADRA2AADRA1ALMNA | |
| SCHEMBL8782180 | 0.80 | ADRA2A (0.69) | MEN1KMT2AADRA2AADRA1AHTR3E | |
| SCHEMBL20855859 | 0.80 | ADRA1A (0.49) | MEN1KMT2AADRA2AADRA1ALMNA | |
| SCHEMBL20855438 | 0.80 | ADRA1A (0.49) | MEN1KMT2AADRA2AADRA1ALMNA | |
| SCHEMBL11040254 | 0.79 | LPAR1 (0.46) | MEN1KMT2AHTR3EHTR3BHTR3A | |
| SCHEMBL10712718 | 0.79 | CNR2 (0.56) | MEN1KMT2ALMNALPAR1CYP2D6 | |
| SCHEMBL16791810 | 0.79 | ADRA2A (0.47) | MEN1KMT2AADRA2AADRA1ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10343985-B2 | Cryopyrin inhibitors for preventing and treating inflammation | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 2019-07-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10343985-B2 | Cryopyrin inhibitors for preventing and treating inflammation | IL1RN, SERPINB1, NFKBIA | MEN1 3064/4885KMT2A 4707/4885ADRA2A 4357/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.