Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 5/20 | 0.81 |
| ▸ | SRC | P12931 | 7/20 | 0.55 |
| ▸ | KDR | P35968 | 6/20 | 0.55 |
| ▸ | MAP4K5 | Q9Y4K4 | 3/20 | 0.53 |
| ▸ | PRKD3 | O94806 | 3/20 | 0.53 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.53 |
| ▸ | PHKG2 | P15735 | 2/20 | 0.53 |
| ▸ | CAMK2G | Q13555 | 2/20 | 0.53 |
| ▸ | CAMK2D | Q13557 | 2/20 | 0.53 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.53 |
| ▸ | HIPK4 | Q8NE63 | 2/20 | 0.53 |
| ▸ | PRKD2 | Q9BZL6 | 2/20 | 0.53 |
| ▸ | SLK | Q9H2G2 | 2/20 | 0.53 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.53 |
| ▸ | STK17A | Q9UEE5 | 2/20 | 0.53 |
| ▸ | MAP2K2 | P36507 | 2/20 | 0.53 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.53 |
| ▸ | PLK4 | O00444 | 1/20 | 0.53 |
| ▸ | PRKCG | P05129 | 1/20 | 0.53 |
| ▸ | CDK2 | P24941 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21136953 | 0.90 | ROCK2 (0.76) | ROCK2KDRMAP4K5PRKD3CHEK2 | |
| SCHEMBL877371 | 0.90 | ROCK2 (1.00) | ROCK2SRCKDRMAP4K5PRKD3 | |
| SCHEMBL877053 | 0.89 | ROCK2 (0.76) | ROCK2SRCKDRMAP4K5PRKD3 | |
| SCHEMBL1724703 | 0.89 | ROCK2 (0.82) | ROCK2SRCKDRMAP4K5PRKD3 | |
| SCHEMBL3794720 | 0.88 | ROCK2 (0.75) | ROCK2SRCKDRMAP4K5PRKD3 | |
| SCHEMBL1724886 | 0.88 | ROCK2 (0.80) | ROCK2SRCKDRMAP4K5PRKD3 | |
| SCHEMBL21136954 | 0.86 | ROCK2 (0.62) | ROCK2KDRMAP4K5PRKD3CHEK2 | |
| SCHEMBL3794722 | 0.85 | ROCK2 (0.71) | ROCK2SRCKDRMAP4K5PRKD3 | |
| SCHEMBL1724850 | 0.85 | ROCK2 (1.00) | ROCK2SRCKDRMAP4K5PRKD3 | |
| SCHEMBL1722249 | 0.84 | ROCK2 (0.87) | ROCK2SRCKDRMAP4K5PRKD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10570123-B2 | Pharmacokinetically improved compounds | SURFACE LOGIX, LLC (US) | 2020-02-25 | — | — | US | disclosed |
| US-20190177311-A1 | PHARMACOKINETICALLY IMPROVED COMPOUNDS | SURFACE LOGIX, INC. | 2019-06-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190177311-A1 | PHARMACOKINETICALLY IMPROVED COMPOUNDS | ROCK2, ROCK1, RHOT2 | ROCK2 1/4885SRC 1809/4885KDR 1005/4885 |
| US-10570123-B2 | Pharmacokinetically improved compounds | ROCK2, ROCK1, RHOT2 | ROCK2 1/4885SRC 1809/4885KDR 1005/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.