Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.56 |
| ▸ | NPC1 | O15118 | 5/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.48 |
| ▸ | STAT3 | P40763 | 1/20 | 0.48 |
| ▸ | STAT1 | P42224 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetamide SCHEMBL27527964 | 0.91 | SMN1; SMN2 (0.51) | RAB9ASMN1; SMN2NPC1RXFP1ALDH1A1 | |
| SCHEMBL28497141 | 0.86 | NPC1 (0.52) | RAB9ASMN1; SMN2NPC1RXFP1ALDH1A1 | |
| SCHEMBL18357054 | 0.82 | RAB9A (0.58) | RAB9ASMN1; SMN2NPC1RXFP1ALDH1A1 | |
| SCHEMBL21137733 | 0.82 | ALDH1A1 (0.59) | RAB9ASMN1; SMN2NPC1RXFP1ALDH1A1 | |
| SCHEMBL22783988 | 0.82 | SMN1; SMN2 (0.53) | RAB9ASMN1; SMN2NPC1RXFP1ALDH1A1 | |
| SCHEMBL22783993 | 0.82 | NPC1 (0.53) | RAB9ASMN1; SMN2NPC1RXFP1ALDH1A1 | |
| SCHEMBL6177219 | 0.81 | ALDH1A1 (0.57) | RAB9ASMN1; SMN2NPC1RXFP1ALDH1A1 | |
| SCHEMBL21137717 | 0.81 | ALDH1A1 (0.57) | RAB9ASMN1; SMN2NPC1RXFP1ALDH1A1 | |
| SCHEMBL8070658 | 0.80 | ALDH1A1 (0.52) | RAB9ASMN1; SMN2NPC1RXFP1ALDH1A1 | |
| SCHEMBL18002935 | 0.79 | SMN1; SMN2 (0.53) | RAB9ASMN1; SMN2NPC1RXFP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200392138-A1 | PESTICIDALLY ACTIVE MESOIONIC HETEROCYCLIC COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2020-12-17 | — | — | US | disclosed |
| WO-2019115404-A1 | PESTICIDALLY ACTIVE MESOIONIC HETEROCYCLIC COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-06-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200392138-A1 | PESTICIDALLY ACTIVE MESOIONIC HETEROCYCLIC COMPOUNDS | DDT, ACHE, MNS1 | RAB9A 1172/4885SMN1; SMN2 487/4885NPC1 2872/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.