SCHEMBL21137896

SCHEMBL21137896

CCCC(=O)N[C@H]1C(O)O[C@H](COC(=O)[C@@H](NC(=O)CNC(=O)OC(C)(C)C)C(C)C)[C@@H](O)[C@@H]1O

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ SDCBP O00560 1/20 0.32
▸ SDC2 P34741 1/20 0.32
▸ PYGB P11216 1/20 0.32
▸ CTSS P25774 1/20 0.31
▸ CTSK P43235 1/20 0.31
▸ KLK5 Q9Y337 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21137891 0.92 CTSK (0.35) PYGBCTSSCTSKKLK5
SCHEMBL21058397 0.92 CTSK (0.35) PYGBCTSSCTSKKLK5
SCHEMBL21138667 0.83 PYGB (0.36) PYGB
Hydrochloric Acid SCHEMBL29777456 0.82 PYGB (0.36) PYGB
SCHEMBL25957442 0.81 CTSK (0.36) PYGBCTSSCTSK
SCHEMBL31353010 0.81 CAPN1 (0.40) PYGBCTSSCTSK
SCHEMBL21137968 0.79 PYGB (0.38) PYGB
SCHEMBL21058338 0.79 MEN1 (0.36) PYGB
SCHEMBL21138004 0.79 MEN1 (0.36) PYGB
SCHEMBL23104926 0.77 PYGB (0.39) PYGB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115215911-B Glucosamine derivative, composition thereof and medical application thereof 润佳(苏州)医药科技有限公司 2024-07-05 — — CN disclosed
US-11718636-B2 Glucosamine derivatives for the prevention or treatment of joint disorders Risen (Suzhou) Pharma Tech Co., Ltd. (CN) 2023-08-08 — — US disclosed
US-11718636-B2 Glucosamine derivatives for the prevention or treatment of joint disorders Risen (Suzhou) Pharma Tech Co., Ltd. (CN) 2023-08-08 — — US disclosed
US-20230227488-A1 GLUCOSAMINE DERIVATIVES AND PHARMACEUTICAL USES THEREOF RISEN SUZHOU PHARMA TECH CO LTD (CN) 2023-07-20 — — US disclosed
US-20230227488-A1 GLUCOSAMINE DERIVATIVES AND PHARMACEUTICAL USES THEREOF RISEN SUZHOU PHARMA TECH CO LTD (CN) 2023-07-20 — — US disclosed
US-11591358-B2 Glucosamine derivatives and pharmaceutical uses thereof Risen (Suzhou) Pharma Tech Co., Ltd. (CN) 2023-02-28 — — US disclosed
CN-115215911-A Glucosamine derivative, composition thereof and medical application thereof 润佳(苏州)医药科技有限公司 2022-10-21 — — CN disclosed
CN-109929001-B Glucosamine derivative, composition thereof and medical application thereof 润佳(苏州)医药科技有限公司 2022-07-08 — — CN disclosed
US-20210079033-A1 GLUCOSAMINE DERIVATIVES FOR THE PREVENTION OR TREATMENT OF JOINT DISORDERS Risen (Suzhou) Pharma Tech Co., Ltd. (CN) 2021-03-18 — — US disclosed
US-20190185502-A1 GLUCOSAMINE DERIVATIVES AND PHARMACEUTICAL USES THEREOF RISEN (SUZHOU) PHARMA TECH CO, LTD. (CN) 2019-06-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210079033-A1 GLUCOSAMINE DERIVATIVES FOR THE PREVENTION OR TREATMENT OF JOINT DISORDERS OGT, UGGT1, GLA SDCBP 2770/4885SDC2 3894/4885PYGB 760/4885
US-11718636-B2 Glucosamine derivatives for the prevention or treatment of joint disorders OGT, UGGT1, GLA SDCBP 2770/4885SDC2 3894/4885PYGB 760/4885
US-20230227488-A1 GLUCOSAMINE DERIVATIVES AND PHARMACEUTICAL USES THEREOF OGT, UGGT1, GLA SDCBP 3911/4885SDC2 4329/4885PYGB 601/4885
US-20190185502-A1 GLUCOSAMINE DERIVATIVES AND PHARMACEUTICAL USES THEREOF OGT, UGGT1, GLA SDCBP 3911/4885SDC2 4329/4885PYGB 601/4885
US-11591358-B2 Glucosamine derivatives and pharmaceutical uses thereof OGT, UGGT1, GLA SDCBP 3911/4885SDC2 4329/4885PYGB 601/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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