Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 2/20 | 0.39 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17137361 | 0.79 | IRAK4 (0.39) | IRAK4ARALDH1A1L3MBTL1 | |
| SCHEMBL21338642 | 0.79 | IRAK4 (0.39) | IRAK4ARALDH1A1L3MBTL1 | |
| SCHEMBL9506108 | 0.73 | CTSD (0.41) | CTSDIRAK4 | |
| SCHEMBL9867293 | 0.73 | CTSD (0.60) | CTSDHDAC1HDAC6 | |
| SCHEMBL9557524 | 0.73 | CTSD (0.41) | CTSDIRAK4 | |
| SCHEMBL9867296 | 0.73 | CTSD (0.60) | CTSDHDAC1HDAC6 | |
| Hydrochloric Acid SCHEMBL9506267 | 0.71 | CTSD (0.40) | CTSDIRAK4 | |
| Hydrochloric Acid SCHEMBL10628796 | 0.71 | CTSD (0.40) | CTSDIRAK4 | |
| SCHEMBL16885242 | 0.71 | CTSD (0.36) | CTSD | |
| SCHEMBL8970887 | 0.69 | CTSD (0.37) | CTSDIRAK4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3724198-B1 | 2-OXO-1-PYRROLIDINYL IMIDAZOTHIADIAZOLE DERIVATIVES | UCB Biopharma SRL (BE) | 2022-02-16 | — | — | EP | disclosed |
| WO-2019115292-A1 | 2-OXO-1-PYRROLIDINYL IMIDAZOTHIADIAZOLE DERIVATIVES | UCB BIOPHARMA SPRL (BE) | 2019-06-20 | — | — | WO | disclosed |