SCHEMBL21138303

SCHEMBL21138303

CCCCOC[C@H]1OC(O)[C@H](NC(=O)CCC)[C@@H](O)[C@@H]1OCCCC

nearest known ligand 0.40

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ GJB2 P29033 4/20 0.40
▸ PYGB P11216 1/20 0.37
▸ MAPK1 P28482 1/20 0.36
▸ SELP P16109 1/20 0.35
▸ GBA1 P04062 4/20 0.34
▸ TLR4 O00206 3/20 0.34
▸ L3MBTL1 Q9Y468 1/20 0.33
▸ SSTR4 P31391 1/20 0.33
▸ NEU1 Q99519 1/20 0.32
▸ NEU2 Q9Y3R4 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21137949 0.88 PYGB (0.47) PYGBMAPK1TLR4
SCHEMBL21138305 0.88 PYGB (0.43) PYGBMAPK1SELPTLR4L3MBTL1
SCHEMBL21137947 0.81 PYGB (0.50) PYGBMAPK1GBA1TLR4
SCHEMBL13456774 0.79 GJB2 (0.49) GJB2GBA1
SCHEMBL13456871 0.79 GJB2 (0.49) GJB2GBA1
SCHEMBL13810618 0.78 GJB2 (0.51) GJB2GBA1
SCHEMBL12085702 0.78 GJB2 (0.51) GJB2GBA1
SCHEMBL21138212 0.77 PYGB (0.42) PYGBMAPK1SELPTLR4L3MBTL1
SCHEMBL21058379 0.76 TLR4 (0.42) PYGBTLR4
SCHEMBL14291824 0.76 GJB2 (0.47) GJB2GBA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11718636-B2 Glucosamine derivatives for the prevention or treatment of joint disorders Risen (Suzhou) Pharma Tech Co., Ltd. (CN) 2023-08-08 — — US disclosed
US-11718636-B2 Glucosamine derivatives for the prevention or treatment of joint disorders Risen (Suzhou) Pharma Tech Co., Ltd. (CN) 2023-08-08 — — US disclosed
US-20230227488-A1 GLUCOSAMINE DERIVATIVES AND PHARMACEUTICAL USES THEREOF RISEN SUZHOU PHARMA TECH CO LTD (CN) 2023-07-20 — — US disclosed
US-20230227488-A1 GLUCOSAMINE DERIVATIVES AND PHARMACEUTICAL USES THEREOF RISEN SUZHOU PHARMA TECH CO LTD (CN) 2023-07-20 — — US disclosed
US-11591358-B2 Glucosamine derivatives and pharmaceutical uses thereof Risen (Suzhou) Pharma Tech Co., Ltd. (CN) 2023-02-28 — — US disclosed
US-20210079033-A1 GLUCOSAMINE DERIVATIVES FOR THE PREVENTION OR TREATMENT OF JOINT DISORDERS Risen (Suzhou) Pharma Tech Co., Ltd. (CN) 2021-03-18 — — US disclosed
US-20190185502-A1 GLUCOSAMINE DERIVATIVES AND PHARMACEUTICAL USES THEREOF RISEN (SUZHOU) PHARMA TECH CO, LTD. (CN) 2019-06-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210079033-A1 GLUCOSAMINE DERIVATIVES FOR THE PREVENTION OR TREATMENT OF JOINT DISORDERS OGT, UGGT1, GLA GJB2 1618/4885PYGB 760/4885MAPK1 887/4885
US-11718636-B2 Glucosamine derivatives for the prevention or treatment of joint disorders OGT, UGGT1, GLA GJB2 1618/4885PYGB 760/4885MAPK1 887/4885
US-20230227488-A1 GLUCOSAMINE DERIVATIVES AND PHARMACEUTICAL USES THEREOF OGT, UGGT1, GLA GJB2 3199/4885PYGB 601/4885MAPK1 846/4885
US-20190185502-A1 GLUCOSAMINE DERIVATIVES AND PHARMACEUTICAL USES THEREOF OGT, UGGT1, GLA GJB2 3199/4885PYGB 601/4885MAPK1 846/4885
US-11591358-B2 Glucosamine derivatives and pharmaceutical uses thereof OGT, UGGT1, GLA GJB2 3199/4885PYGB 601/4885MAPK1 846/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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