Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | THRB | P10828 | 1/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 4/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | ABL1 | P00519 | 1/20 | 0.50 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11488922 | 1.00 | ALDH1A1 (0.61) | ALDH1A1TSHRTHRBATML3MBTL1 | |
| SCHEMBL11402027 | 1.00 | ALDH1A1 (0.61) | ALDH1A1TSHRTHRBATML3MBTL1 | |
| SCHEMBL8710504 | 1.00 | ALDH1A1 (0.61) | ALDH1A1TSHRTHRBATML3MBTL1 | |
| SCHEMBL675456 | 1.00 | ALDH1A1 (0.61) | ALDH1A1TSHRTHRBATML3MBTL1 | |
| SCHEMBL1292196 | 1.00 | ALDH1A1 (0.61) | ALDH1A1TSHRTHRBATML3MBTL1 | |
| Hydrochloric Acid SCHEMBL1770298 | 0.98 | ALDH1A1 (0.59) | ALDH1A1TSHRTHRBATML3MBTL1 | |
| Bromide SCHEMBL31591109 | 0.98 | ALDH1A1 (0.59) | ALDH1A1TSHRTHRBATML3MBTL1 | |
| SCHEMBL2223429 | 0.98 | TSHR (0.63) | ALDH1A1TSHRTHRBATML3MBTL1 | |
| SCHEMBL3635136 | 0.98 | TSHR (0.63) | ALDH1A1TSHRTHRBATML3MBTL1 | |
| Butane SCHEMBL7959791 | 0.96 | ALDH1A1 (0.58) | ALDH1A1TSHRTHRBATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3505171-A1 | BICYCLIC NITROGENATED HETEROCYCLIC COMPOUND | Mitsubishi Tanabe Pharma Corporation (JP) | 2019-07-03 | — | — | EP | disclosed |
| US-20190185479-A1 | BICYCLIC NITROGENATED HETEROCYCLIC COMPOUND | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2019-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190185479-A1 | BICYCLIC NITROGENATED HETEROCYCLIC COMPOUND | PDE7B, PDE3A, PDE7A | ALDH1A1 1644/4885TSHR 4597/4885THRB 4781/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.