Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 4/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | ABL1 | P00519 | 1/20 | 0.52 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | NOS3 | P29474 | 1/20 | 0.49 |
| ▸ | NOS2 | P35228 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3635136 | 1.00 | TSHR (0.63) | TSHRALDH1A1POLBSMN1; SMN2HTT | |
| Hydrochloric Acid SCHEMBL19031025 | 0.98 | TSHR (0.61) | TSHRALDH1A1POLBSMN1; SMN2HTT | |
| SCHEMBL11402027 | 0.98 | ALDH1A1 (0.61) | TSHRALDH1A1POLBSMN1; SMN2HTT | |
| SCHEMBL21138457 | 0.98 | ALDH1A1 (0.61) | TSHRALDH1A1POLBSMN1; SMN2HTT | |
| SCHEMBL675456 | 0.98 | ALDH1A1 (0.61) | TSHRALDH1A1POLBSMN1; SMN2HTT | |
| SCHEMBL8710504 | 0.98 | ALDH1A1 (0.61) | TSHRALDH1A1POLBSMN1; SMN2HTT | |
| SCHEMBL1292196 | 0.98 | ALDH1A1 (0.61) | TSHRALDH1A1POLBSMN1; SMN2HTT | |
| SCHEMBL11488922 | 0.98 | ALDH1A1 (0.61) | TSHRALDH1A1POLBSMN1; SMN2HTT | |
| Bromide SCHEMBL31591109 | 0.95 | ALDH1A1 (0.59) | TSHRALDH1A1POLBSMN1; SMN2HTT | |
| Hydrochloric Acid SCHEMBL1770298 | 0.95 | ALDH1A1 (0.59) | TSHRALDH1A1POLBSMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 243 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115335369-B | GEM-disubstituted piperidine melanocortin subtype-2 receptor (MC 2R) antagonists and uses thereof | 克林提克斯医药股份有限公司 | 2024-07-02 | — | — | CN | claimed |
| CN-115335369-A | GEM-disubstituted piperidine melanocortin subtype-2 receptor (MC 2R) antagonists and uses thereof | 克林提克斯医药股份有限公司 | 2022-11-11 | — | — | CN | claimed |
| CN-104918939-B | Purine inhibitors of human phosphatidylinositol 3-kinase | 默沙东公司 | 2018-08-28 | — | — | CN | claimed |
| CN-103435535-A | Preparation method of R-proline having cyclopropane structure | UNIV JIAXING | 2013-12-11 | — | — | CN | claimed |
| CN-103435534-A | Preparation method of S-proline having cyclopropane structure | UNIV JIAXING | 2013-12-11 | — | — | CN | claimed |
| EP-0188805-B1 | 1,3-DITHIOLE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1989-09-06 | — | — | EP | claimed |
| CN-119409710-A | Oxamide substituted hepatitis b virus tricyclic inhibitors | 圣拉斐尔医院有限公司 | 2025-02-11 | — | — | CN | disclosed |
| CN-114555608-B | Oxamide substituted hepatitis b virus tricyclic inhibitors | 圣拉斐尔医院有限公司 | 2024-11-01 | — | — | CN | disclosed |
| CN-114667282-B | Pyrimidine amide compounds and methods of treating cancer | 昊运股份有限公司 | 2024-09-03 | — | — | CN | disclosed |
| CN-115335369-B | GEM-disubstituted piperidine melanocortin subtype-2 receptor (MC 2R) antagonists and uses thereof | 克林提克斯医药股份有限公司 | 2024-07-02 | — | — | CN | disclosed |
| WO-2024081363-A1 | COMPOSITION COMPRISING A FIRST RAS INHIBITOR, SECOND RAS INHIBITOR AND A SHP2 INHIBITOR FOR USE IN THE TREATMENT OF CANCER | Revolution Medicines, Inc. (US) | 2024-04-18 | — | — | WO | disclosed |
| CN-113272309-B | Tricyclic inhibitors of hepatitis b virus | 圣拉斐尔医院有限公司 | 2024-02-23 | — | — | CN | disclosed |
| CN-111801100-B | 7-substituted sulfoimidoyl purinone compounds and derivatives for the treatment and prevention of liver cancer | 豪夫迈·罗氏有限公司 | 2023-10-24 | — | — | CN | disclosed |
| EP-0586229-A1 | 3-Hydroxy-3-(subst-akyl)-pyrrolidines as 5-lipoxygenase inhibitors | ZENECA LIMITED (GB) | 1994-03-09 | — | — | EP | disclosed |
| US-5262189-A | Cereals | NESTEC S.A. (CH) | 1993-11-16 | — | — | US | disclosed |
| EP-0307142-A1 | Thiadiazoles useful in the treatment of senile dementia | MERCK SHARP & DOHME LTD. (GB) | 1989-03-15 | — | — | EP | disclosed |
| US-4483991-A | Hypotensive agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1984-11-20 | — | — | US | disclosed |
| US-4234484-A | FROM ALKOXYLATED CYCLIC AMIDES USING AS A CATALYST A QUATERNARY AMMONIUM OR ALKALI METAL SALT OF TETRAFLUOROBORIC OR HEXAFLUOROPHOSPHORIC ACID | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-11-18 | — | — | US | disclosed |
| US-4149941-A | ELECTROLYTIC ALKOXYLATION | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-04-17 | — | — | US | disclosed |
| US-4118500-A | Fungicidal alkoxy mono- and dialkoxy N-substituted cyclic amines | HOECHST AKTIENGESELLSCHAFT (DE) | 1978-10-03 | — | — | US | disclosed |