Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 4/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | ABL1 | P00519 | 1/20 | 0.52 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | NOS3 | P29474 | 1/20 | 0.49 |
| ▸ | NOS2 | P35228 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2223429 | 1.00 | TSHR (0.63) | TSHRALDH1A1POLBSMN1; SMN2HTT | |
| Hydrochloric Acid SCHEMBL19031025 | 0.98 | TSHR (0.61) | TSHRALDH1A1POLBSMN1; SMN2HTT | |
| SCHEMBL11402027 | 0.98 | ALDH1A1 (0.61) | TSHRALDH1A1POLBSMN1; SMN2HTT | |
| SCHEMBL21138457 | 0.98 | ALDH1A1 (0.61) | TSHRALDH1A1POLBSMN1; SMN2HTT | |
| SCHEMBL675456 | 0.98 | ALDH1A1 (0.61) | TSHRALDH1A1POLBSMN1; SMN2HTT | |
| SCHEMBL8710504 | 0.98 | ALDH1A1 (0.61) | TSHRALDH1A1POLBSMN1; SMN2HTT | |
| SCHEMBL1292196 | 0.98 | ALDH1A1 (0.61) | TSHRALDH1A1POLBSMN1; SMN2HTT | |
| SCHEMBL11488922 | 0.98 | ALDH1A1 (0.61) | TSHRALDH1A1POLBSMN1; SMN2HTT | |
| Bromide SCHEMBL31591109 | 0.95 | ALDH1A1 (0.59) | TSHRALDH1A1POLBSMN1; SMN2HTT | |
| Hydrochloric Acid SCHEMBL1770298 | 0.95 | ALDH1A1 (0.59) | TSHRALDH1A1POLBSMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2155687-A1 | DIACYLGLYCEROL ACYLTRANSFERASE INHIBITORS | Via Pharmaceuticals, Inc. (US) | 2010-02-24 | — | — | EP | disclosed |
| WO-2008141976-A1 | DIACYLGLYCEROL ACYLTRANSFERASE INHIBITORS | VIA PHARMACEUTICALS, INC. (US) | 2008-11-27 | — | — | WO | disclosed |