Fluoride

Fluoride

SCHEMBL2113850

CCN(CC)CC.F.F.F.F

nearest known ligand 0.36

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.36
MGLL Q99685 1/20 0.33
HRH3 Q9Y5N1 1/20 0.33
CYP2C9 P11712 1/20 0.32
HPGD P15428 1/20 0.32
HSD17B10 Q99714 1/20 0.32
KDM4E B2RXH2 1/20 0.32
MEN1 O00255 1/20 0.32
POLB P06746 1/20 0.32
MAPT P10636 1/20 0.32
THRB P10828 1/20 0.32
APEX1 P27695 1/20 0.32
MAPK1 P28482 1/20 0.32
HTT P42858 1/20 0.32
RECQL P46063 1/20 0.32
CACNA1B Q00975 1/20 0.32
APBA1 Q02410 1/20 0.32
KMT2A Q03164 1/20 0.32
MCL1 Q07820 1/20 0.32
HKDC1 Q2TB90 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluoride SCHEMBL13581787 1.00 ALDH1A1 (0.36) ALDH1A1MGLLHRH3CYP2C9HPGD
Fluoride SCHEMBL99441 1.00
Fluoride SCHEMBL22345959 1.00 ALDH1A1 (0.36) ALDH1A1MGLLHRH3CYP2C9HPGD
Fluoride SCHEMBL28937464 1.00 ALDH1A1 (0.36) ALDH1A1MGLLHRH3CYP2C9HPGD
Fluoride SCHEMBL2116095 1.00
Fluoride SCHEMBL3420981 1.00 ALDH1A1 (0.36) ALDH1A1MGLLHRH3CYP2C9HPGD
Fluoride SCHEMBL21513 1.00 ALDH1A1 (0.36) ALDH1A1MGLLHRH3CYP2C9HPGD
Hydrochloric Acid SCHEMBL23277117 0.95 ALDH1A1 (0.33) ALDH1A1MGLLHRH3CYP2C9HPGD
Fluoride SCHEMBL10581757 0.95 ALDH1A1 (0.33) ALDH1A1MGLLHRH3CYP2C9HPGD
Fluoride SCHEMBL1263596 0.95

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118702075-A Preparation method of phosphorus trifluoride 天津绿菱气体股份有限公司 2024-09-27 CN claimed
CN-118702075-A Preparation method of phosphorus trifluoride 天津绿菱气体股份有限公司 2024-09-27 CN disclosed
EP-2053054-B1 METHOD FOR INTRODUCING NUCLEIC-ACID-PROTECTING GROUP NIPPON SHINYAKU CO LTD (JP) 2014-12-17 EP disclosed
US-8158774-B2 Method for introducing a nucleic-acid protecting group NIPPON SHINYAKU CO., LTD. (JP) 2012-04-17 US disclosed
US-20090312534-A1 METHOD FOR REMOVAL OF NUCLEIC ACID-PROTECTING GROUP NIPPON SHINYAKU CO., LTD. (JP) 2009-12-17 US disclosed
US-20090286970-A1 METHOD FOR INTRODUCING A NUCLEIC-ACID PROTECTING GROUP NIPPON SHINYAKU CO., LTD. (JP) 2009-11-19 US disclosed
EP-2053054-A1 METHOD FOR INTRODUCING NUCLEIC-ACID-PROTECTING GROUP Nippon Shinyaku Co., Ltd. (JP) 2009-04-29 EP disclosed
EP-1995252-A1 METHOD FOR REMOVAL OF NUCLEIC ACID-PROTECTING GROUP Nippon Shinyaku Co., Ltd. (JP) 2008-11-26 EP disclosed
CN-101189248-A Novel phosphorus-containing thyromimetics METABASIS THERAPEUTICS INC (US) 2008-05-28 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090312534-A1 METHOD FOR REMOVAL OF NUCLEIC ACID-PROTECTING GROUP NSUN2, RNASEH1, RNASE1 ALDH1A1 1799/4885MGLL 2670/4885HRH3 1715/4885
US-20090286970-A1 METHOD FOR INTRODUCING A NUCLEIC-ACID PROTECTING GROUP RNASEH1, SNRPB2, SNRPA1 ALDH1A1 591/4885MGLL 4415/4885HRH3 812/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.