Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 3/20 | 0.56 |
| ▸ | HTR2C | P28335 | 7/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 2/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | AXL | P30530 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.41 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ACVR1B | P36896 | 1/20 | 0.40 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.40 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28875272 | 0.84 | ADRB2 (0.45) | ADRB2ADORA2AADORA1KMT2ATLR7 | |
| SCHEMBL28495169 | 0.80 | ADRB2 (0.41) | ADRB2ADORA2AADORA1KMT2ATLR7 | |
| Hydrochloric Acid SCHEMBL23359877 | 0.76 | ADRB2 (0.52) | ADRB2HTR2CADORA2AADORA1KMT2A | |
| Hydrochloric Acid SCHEMBL29862943 | 0.76 | ADRB2 (0.52) | ADRB2HTR2CADORA2AADORA1KMT2A | |
| SCHEMBL21138824 | 0.75 | HTR2C (0.50) | ADRB2HTR2CKMT2ACYP1A2HTR6 | |
| SCHEMBL22648456 | 0.75 | HTR2C (0.40) | ADRB2HTR2CKMT2AHTR6MEN1 | |
| SCHEMBL19297014 | 0.73 | TLR7 (0.51) | HTR2CADORA2AKMT2ACYP1A2CYP2C19 | |
| SCHEMBL8563546 | 0.73 | HTR2C (0.40) | ADRB2HTR2CKMT2AHTR6MEN1 | |
| SCHEMBL2711296 | 0.72 | ADRB2 (1.00) | ADRB2HTR2CCYP1A2HTR6ADRA2A | |
| SCHEMBL30058924 | 0.72 | ADRB2 (1.00) | ADRB2HTR2CCYP1A2HTR6ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200352931-A1 | OXALAMIDES AS MODULATORS OF INDOLEAMINE 2,3-DIOXYGENASE | Phenex Discovery Verwaltungs-GmbH (DE) | 2020-11-12 | — | — | US | disclosed |
| WO-2019115586-A1 | OXALAMIDES AS MODULATORS OF INDOLEAMINE 2,3-DIOXYGENASE | Phenex Discovery Verwaltungs-GmbH (DE) | 2019-06-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200352931-A1 | OXALAMIDES AS MODULATORS OF INDOLEAMINE 2,3-DIOXYGENASE | IDO1, IDO2, INMT | ADRB2 2424/4885HTR2C 672/4885ADORA2A 1208/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.