Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.40 |
| ▸ | HTR6 | P50406 | 2/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.39 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8567840 | 0.76 | POLB (0.47) | MEN1KMT2ASLC18A3SIGMAR1 | |
| SCHEMBL21138823 | 0.73 | ADRB2 (0.56) | HTR2CHTR6ADRB2MEN1KMT2A | |
| SCHEMBL21138824 | 0.73 | HTR2C (0.50) | HTR2CHTR6ADRB2MEN1KMT2A | |
| SCHEMBL8562365 | 0.73 | ACHE (0.40) | HTR2CHTR6MEN1KMT2ASLC18A3 | |
| SCHEMBL8597133 | 0.72 | HTR2A (0.39) | HTR2CMEN1KMT2ASLC18A3SIGMAR1 | |
| SCHEMBL8562847 | 0.72 | ACHE (0.42) | HTR6MEN1KMT2ASLC18A3SIGMAR1 | |
| SCHEMBL3298254 | 0.70 | KMT2A (0.54) | MEN1KMT2A | |
| SCHEMBL22648456 | 0.70 | HTR2C (0.40) | HTR2CHTR6ADRB2MEN1KMT2A | |
| SCHEMBL8569955 | 0.69 | KMT2A (0.42) | MEN1KMT2A | |
| SCHEMBL3956436 | 0.69 | NCF1 (0.51) | MEN1KMT2ASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |