SCHEMBL21140708

SCHEMBL21140708

Cc1ccc2c3c(oc2c1)CCCC3

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 2/20 0.53
CYP1A2 P05177 2/20 0.50
CYP3A4 P08684 1/20 0.50
CYP2C19 P33261 1/20 0.50
MAPT P10636 5/20 0.43
TP53 P04637 2/20 0.43
KDM4E B2RXH2 3/20 0.42
TSHR P16473 2/20 0.42
ALDH1A1 P00352 2/20 0.42
GAA P10253 2/20 0.42
HPGD P15428 2/20 0.42
GLA P06280 1/20 0.42
CASP1 P29466 1/20 0.42
CASP7 P55210 1/20 0.42
HSD17B10 Q99714 1/20 0.42
MAPK1 P28482 1/20 0.41
HTT P42858 1/20 0.41
DRD2 P14416 2/20 0.41
DRD4 P21917 2/20 0.41
MAOB P27338 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10099058 0.85 CYP1A2 (0.64) MAOACYP1A2CYP3A4CYP2C19MAPT
SCHEMBL7532636 0.81 ALDH1A1 (0.67) MAOACYP1A2MAPTKDM4ETSHR
SCHEMBL3143409 0.78 CYP1A2 (0.74) MAOACYP1A2CYP3A4CYP2C19MAPT
SCHEMBL3144077 0.77 MAPT (0.52) MAOACYP1A2CYP3A4CYP2C19MAPT
SCHEMBL10187520 0.75 CYP1A2 (0.47) MAOACYP1A2CYP3A4CYP2C19MAPT
SCHEMBL25772114 0.74 NQO1 (0.42) CYP1A2KDM4ETSHRALDH1A1GAA
SCHEMBL28798820 0.73 PIM1 (0.65) MAOACYP1A2CYP2C19KDM4EALDH1A1
SCHEMBL9927267 0.73 MAOB (0.53) CYP1A2MAPTTP53KDM4EALDH1A1
SCHEMBL313890 0.72 CYP3A4 (0.56) MAOACYP1A2CYP3A4CYP2C19MAPT
SCHEMBL6579518 0.71 HTR6 (0.49) MAOACYP1A2CYP3A4CYP2C19MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3502107-A1 1-AMINODIBENZOFURAN-BASED COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME Samsung Display Co., Ltd. (KR) 2019-06-26 EP disclosed