Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHCY | P23526 | 4/20 | 0.41 |
| ▸ | NT5E | P21589 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | CHKA | P35790 | 3/20 | 0.35 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.33 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.32 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.32 |
| ▸ | PNP | P00491 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21058180 | 0.86 | AHCY (0.39) | AHCYNT5ELMNAHIF1ACA5A | |
| SCHEMBL21140826 | 0.85 | AHCY (0.42) | AHCYNT5ELMNAHIF1ACA5A | |
| SCHEMBL21140823 | 0.84 | AHCY (0.46) | AHCYNT5ELMNAHIF1ACA5A | |
| SCHEMBL21141081 | 0.84 | AHCY (0.41) | AHCYNT5ELMNAHIF1ACA5A | |
| SCHEMBL28689543 | 0.83 | AHCY (0.40) | AHCYNT5ELMNAHIF1ACA5A | |
| SCHEMBL25395202 | 0.83 | AHCY (0.46) | AHCYNT5ELMNAHIF1ACA5A | |
| SCHEMBL26274323 | 0.83 | AHCY (0.46) | AHCYNT5ELMNAHIF1ACA5A | |
| SCHEMBL25402050 | 0.81 | AHCY (0.34) | AHCYNT5ELMNAHIF1ACA5A | |
| SCHEMBL21057978 | 0.80 | AHCY (0.40) | AHCYNT5ELMNAHIF1ACA5A | |
| SCHEMBL24822036 | 0.79 | AHCY (0.42) | AHCYNT5ELMNAHIF1ACA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190185508-A1 | DEUTERATED NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2019-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190185508-A1 | DEUTERATED NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS | DUT, DIMT1, POLRMT | AHCY 525/4885NT5E 1053/4885LMNA 3345/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.