SCHEMBL21141065

SCHEMBL21141065

CC1(C)c2ccccc2-c2c(N(c3ccc4c(c3)-c3ccccc3-c3ccccc3-c3ccccc3-4)c3ccc4sc5ccccc5c4c3)cccc21

nearest known ligand 0.32

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 1/20 0.32
ALDH1A1 P00352 1/20 0.31
POLB P06746 1/20 0.31
MAPT P10636 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
PDK2 Q15119 1/20 0.31
ALK Q9UM73 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17690167 0.94 ALK (0.32) GPR3ALDH1A1POLBMAPTTDP1
SCHEMBL21141229 0.93 ALDH1A1 (0.34) GPR3ALDH1A1POLBMAPTTDP1
SCHEMBL25145390 0.91
SCHEMBL16544679 0.89 ALK (0.30) ALK
SCHEMBL21141227 0.89 ALOX5 (0.34) PDK2
SCHEMBL21141156 0.89 GPR3 (0.32) GPR3ALDH1A1POLBMAPTTDP1
SCHEMBL26060102 0.88
SCHEMBL25889821 0.88 MEN1 (0.31) POLBMAPTTDP1
SCHEMBL25145448 0.88
SCHEMBL17690144 0.88 ALDH1A1 (0.33) GPR3ALDH1A1POLBMAPTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11512038-B2 Tetraphenylene triarylamine compounds Beijing Summer Sprout Technology Co., Ltd. (CN) 2022-11-29 US disclosed
US-20190185412-A1 TETRAPHENYLENE TRIARYLAMINE COMPOUNDS Beijing Summer Sprout Technology Co., Ltd. (CN) 2019-06-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11512038-B2 Tetraphenylene triarylamine compounds OCIAD2, OCIAD1, SLC7A5 GPR3 1825/4885ALDH1A1 2637/4885POLB 916/4885
US-20190185412-A1 TETRAPHENYLENE TRIARYLAMINE COMPOUNDS OCIAD2, OCIAD1, SLC7A5 GPR3 1825/4885ALDH1A1 2637/4885POLB 916/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.