SCHEMBL211430

SCHEMBL211430

C[Si]1(C)CCCC(c2ccccc2)O1

nearest known ligand 0.42

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.42
SLC6A2 P23975 1/20 0.36
SLC6A4 P31645 1/20 0.36
SLC6A3 Q01959 1/20 0.36
CHRNB2 P17787 1/20 0.34
CHRNB4 P30926 1/20 0.34
CHRNA3 P32297 1/20 0.34
CHRNA7 P36544 1/20 0.34
CHRNA4 P43681 1/20 0.34
KDM1A O60341 2/20 0.33
MAOA P21397 2/20 0.33
MAOB P27338 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28138890 0.98 TSHR (0.41) TSHRSLC6A2SLC6A4SLC6A3CHRNB2
SCHEMBL6061281 0.90
SCHEMBL29289461 0.82 TSHR (0.39) TSHRSLC6A2SLC6A4SLC6A3CHRNB2
SCHEMBL2233573 0.81 TSHR (0.38) TSHRSLC6A2SLC6A4SLC6A3CHRNB2
SCHEMBL1694289 0.78 TSHR (0.36) TSHRSLC6A2SLC6A4SLC6A3CHRNB2
SCHEMBL28141206 0.77 TSHR (0.38) TSHRSLC6A2SLC6A4SLC6A3CHRNB2
SCHEMBL27586839 0.77 TSHR (0.35) TSHRSLC6A2SLC6A4SLC6A3KDM1A
SCHEMBL913096 0.76 TSHR (0.41) TSHRSLC6A2SLC6A4SLC6A3
SCHEMBL11564082 0.76 HTR2C (0.36) SLC6A2SLC6A4SLC6A3KDM1A
SCHEMBL11562602 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 368 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12614943-B2 Electrical operating means having an insulation system, and method for producing the insulation system SIEMENS AKTIENGESELLSCHAFT (DE) 2026-04-28 US claimed
US-20240400858-A1 HIGH CRACK THRESHOLD PLANARIZING COATINGS AND PROCESSES TO FILL WIDE AND DEEP TRENCHES FOR SILICONE WAFERS SOLSTICE ADVANCED MATERIALS US, INC. 2024-12-05 US claimed
WO-2024243005-A1 HIGH CRACK THRESHOLD PLANARIZING COATINGS AND PROCESSES TO FILL WIDE AND DEEP TRENCHES FOR SILICONE WAFERS HONEYWELL INTERNATIONAL INC. (US) 2024-11-28 WO claimed
CN-113730297-B Pearlescent no-wash hair care essence 广州市衡拓贸易有限公司 2023-03-31 CN claimed
CN-115778855-A Lipstick and its preparation method 上海臻臣化妆品有限公司 2023-03-14 CN claimed
US-20220029491-A1 Electrical Operating Means Having an Insulation System, and Method for Producing the Insulation System SIEMENS AKTIENGESELLSCHAFT (DE) 2022-01-27 US claimed
EP-3844218-A1 ELECTRICAL OPERATING MEANS HAVING AN INSULATION SYSTEM, AND METHOD FOR PRODUCING THE INSULATION SYSTEM Siemens Aktiengesellschaft (DE) 2021-07-07 EP claimed
CN-112996852-A Electrical device with insulation system and method for producing an insulation system 西门子股份公司 2021-06-18 CN claimed
US-10626435-B2 Nanofluidic device for isolating, growing, and characterizing microbial cells NORTHEASTERN UNIVERSITY (US) 2020-04-21 US claimed
US-20180243344-A1 OXYGENATED DEMINERALIZED BONE MATRIX FOR USE IN BONE GROWTH YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM, LTD. (IL) 2018-08-30 US claimed
CN-102300898-A Cosmetic composition comprising an aqueous dispersion of polysiloxane/polyurea and a silane and a method for cosmetic treatment 2011-12-28 CN claimed
CN-101854959-A Silicone gel-based compositions for wound healing and scar reduction VALEANT PHARMACEUTICALS INT 2010-10-06 CN claimed
CN-101366687-A Anhydrous cosmetic composition comprising a pressure-sensitive adhesive silicone copolymer, a volatile silicone and a particular fluid silicone OREAL (FR) 2009-02-18 CN claimed
CN-1853611-A Polymer particle dispersion, cosmetic compositions comprising it and cosmetic process using it OREAL (FR) 2006-11-01 CN claimed
CN-1158061-C Alkyl non volatile oil cosmetic composition for preventing shading �ź㴫 2004-07-21 CN claimed
CN-1394134-A Matt cosmetic composition comprising non-volatile hydrocarbon oil and inert particulate phase OREAL (FR) 2003-01-29 CN claimed
CN-1302596-A Alkyl non volatile oil cosmetic composition for preventing shading OREAL (FR) 2001-07-11 CN claimed
CN-1240639-A Composition of olefin copolymer comprising controlled crystallization and use of such coplymer OREAL (FR) 2000-01-12 CN claimed
EP-0679388-B1 Cosmetic and/or dermatologic skin depigmentation composition and its use OREAL (FR) 1998-10-07 EP claimed
EP-0679388-A1 Cosmetic and/or dermatologic skin depigmentation composition and its use L'OREAL (FR) 1995-11-02 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12614943-B2 Electrical operating means having an insulation system, and method for producing the insulation system SCO2, RAE1, FTO TSHR 1696/4885SLC6A2 3497/4885SLC6A4 3905/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.