SCHEMBL2233573

SCHEMBL2233573

C[Si]1(c2ccccc2)CCCC(c2ccccc2)O1

nearest known ligand 0.38

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.38
SLC6A2 P23975 1/20 0.33
SLC6A4 P31645 1/20 0.33
SLC6A3 Q01959 1/20 0.33
CHRNB2 P17787 1/20 0.32
CHRNB4 P30926 1/20 0.32
CHRNA3 P32297 1/20 0.32
CHRNA7 P36544 1/20 0.32
CHRNA4 P43681 1/20 0.32
KDM1A O60341 2/20 0.31
MAOA P21397 2/20 0.31
MAOB P27338 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL211430 0.81 TSHR (0.42) TSHRSLC6A2SLC6A4SLC6A3CHRNB2
SCHEMBL1326144 0.79
SCHEMBL28138890 0.79 TSHR (0.41) TSHRSLC6A2SLC6A4SLC6A3CHRNB2
SCHEMBL913096 0.79 TSHR (0.41) TSHRSLC6A2SLC6A4SLC6A3
SCHEMBL9750709 0.78 TSHR (0.39) TSHRSLC6A2SLC6A4SLC6A3
SCHEMBL28596049 0.78 TSHR (0.39) TSHRSLC6A2SLC6A4SLC6A3
SCHEMBL29289461 0.78 TSHR (0.39) TSHRSLC6A2SLC6A4SLC6A3CHRNB2
SCHEMBL28894979 0.77 TSHR (0.38) TSHRSLC6A2SLC6A4SLC6A3
SCHEMBL8427879 0.76 SLC6A2 (0.37) TSHRSLC6A2SLC6A4SLC6A3KDM1A
SCHEMBL8386212 0.76 TSHR (0.35) TSHRSLC6A2SLC6A4SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3941978-A1 SILOXANE ADDITIVE MANUFACTURING COMPOSITION Spectroplast AG (CH) 2022-01-26 EP claimed
WO-2020187891-A1 SILOXANE ADDITIVE MANUFACTURING COMPOSITION SPECTROPLAST AG (CH) 2020-09-24 WO claimed
CN-119592182-A Polyether organic silicon composite material and method for preparing synthetic leather by using same 东莞市雄驰电子有限公司 2025-03-11 CN disclosed
US-8946353-B2 Curable organopolysiloxane composition, optical semiconductor element sealant, and optical semiconductor device DOW CORNING TORAY CO. LTD. (JP) 2015-02-03 US disclosed
US-8440776-B2 Lens-forming silicone resin composition and silicone lens SHIN-ETSU CHEMICAL CO., LTD. (JP) 2013-05-14 US disclosed
US-8204424-B2 Cleaning blade for electrophotographic device and method for manufacturing the same BANDO CHEMICAL INDUSTRIES, LTD. (JP) 2012-06-19 US disclosed
US-20110254047-A1 Curable Organopolysiloxane Composition, Optical Semiconductor Element Sealant, And Optical Semiconductor Device DOW TORAY CO., LTD. (JP) 2011-10-20 US disclosed
EP-2352794-A1 CURABLE ORGANOPOLYSILOXANE COMPOSITION, OPTICAL SEMICONDUCTOR ELEMENT SEALANT, AND OPTICAL SEMICONDUCTOR DEVICE Dow Corning Toray Co., Ltd. (JP) 2011-08-10 EP disclosed
US-7829651-B2 Lens-forming silicone resin composition and silicone lens SHIN-ETSU CHEMICAL CO., LTD. (JP) 2010-11-09 US disclosed
US-20100197870-A1 LENS-FORMING SILICONE RESIN COMPOSITION AND SILICONE LENS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2010-08-05 US disclosed
US-20100150628-A1 CLEANING BLADE FOR ELECTROPHOTOGRAPHIC DEVICE AND METHOD FOR MANUFACTURING THE SAME BANDO CHEMICAL INDUSTRIES, LTD. (JP) 2010-06-17 US disclosed
US-5747009-A STABLE WATER IN OIL EMULSION; COLORING THE SKIN L'OREAL (FR) 1998-05-05 US disclosed
EP-0604249-B1 Compositions containing dihydroxyacetone and their cosmetic use OREAL (FR) 1997-04-16 EP disclosed
EP-0691839-B1 DIHYDROXYACETONE-BASED EMULSION AND ITS USE IN COSMETICS OREAL (FR) 1996-12-04 EP disclosed
EP-0691839-A1 DIHYDROXYACETONE-BASED EMULSION AND ITS USE IN COSMETICS OREAL (FR) 1996-01-17 EP disclosed
WO-1994022418-A1 DIHYDROXYACETONE-BASED EMULSION AND ITS USE IN COSMETICS L'OREAL (FR) 1994-10-13 WO disclosed
EP-0604249-A1 Compositions containing dihydroxyacetone and their cosmetic use L'OREAL (FR) 1994-06-29 EP disclosed
EP-0394918-A2 Curable phosphazene compositions and coated articles IDEMITSU PETROCHEMICAL CO. LTD. (JP) 1990-10-31 EP disclosed
EP-0094153-A2 Inherently wettable silicone resin optical devices DOW CORNING CORPORATION (US) 1983-11-16 EP disclosed
US-3974122-A Heat-curable silicone resin compositions SHIN-ETSU CHEMICAL CO., LTD. (JA) 1976-08-10 US disclosed