SCHEMBL21144228

SCHEMBL21144228

CCCCCCc1nnco1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 2/20 0.39
ALDH1A1 P00352 2/20 0.36
MTNR1A P48039 1/20 0.35
MTNR1B P49286 1/20 0.35
PTGS2 P35354 3/20 0.35
ESR1 P03372 2/20 0.35
ADRA2A P08913 2/20 0.35
ADORA3 P0DMS8 2/20 0.35
TACR2 P21452 2/20 0.35
SLC6A2 P23975 2/20 0.35
SLC6A4 P31645 2/20 0.35
SLC6A3 Q01959 2/20 0.35
KDM4E B2RXH2 1/20 0.35
LMNA P02545 1/20 0.35
SHBG P04278 1/20 0.35
TP53 P04637 1/20 0.35
CYP3A4 P08684 1/20 0.35
HSPD1 P10809 1/20 0.35
ADRB3 P13945 1/20 0.35
HTR2C P28335 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21210736 1.00 KCNH2 (0.39) KCNH2ALDH1A1MTNR1AMTNR1BPTGS2
SCHEMBL4611727 1.00 KCNH2 (0.39) KCNH2ALDH1A1MTNR1AMTNR1BPTGS2
SCHEMBL1780408 0.98 KCNH2 (0.36) KCNH2ALDH1A1MTNR1AMTNR1BPTGS2
SCHEMBL4610821 0.89 EPHX2 (0.41) CES1
SCHEMBL2090142 0.79 CES1 (0.37) MTNR1AMTNR1BMAPTCES1DAGLA
SCHEMBL2096131 0.79 CES1 (0.37) MTNR1AMTNR1BMAPTCES1DAGLA
SCHEMBL2090144 0.79 CES1 (0.37) MTNR1AMTNR1BTBXAS1MAPTCES1
SCHEMBL2095686 0.76 MTNR1A (0.40) ALDH1A1MTNR1AMTNR1BKDM4EMAPT
SCHEMBL2092256 0.72 MTNR1A (0.37) MTNR1AMTNR1B
SCHEMBL23488070 0.69 CTSK (0.38) LMNACTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119638629-A Low-temperature molten salt, preparation method thereof and application method thereof in electrolytic aluminum 安阳工学院 2025-03-18 CN disclosed
CN-117597342-A Pyrrolidine derivative, pharmaceutical composition and application thereof in medicine 成都百裕制药股份有限公司 2024-02-23 CN disclosed
US-10737280-B2 Method of using flotation collector containing azolethione structure CENTRAL SOUTH UNIVERSITY (CN) 2020-08-11 US disclosed
US-20190217310-A1 METHOD OF USING FLOTATION COLLECTOR CONTAINING AZOLETHIONE STRUCTURE CENTRAL SOUTH UNIVERSITY (CN) 2019-07-18 US disclosed