Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 2/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.32 |
| ▸ | TACR2 | P21452 | 2/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4611727 | 0.98 | KCNH2 (0.39) | KCNH2MTNR1AMTNR1BCTSKCYP3A4 | |
| SCHEMBL21144228 | 0.98 | KCNH2 (0.39) | KCNH2MTNR1AMTNR1BCTSKCYP3A4 | |
| SCHEMBL21210736 | 0.98 | KCNH2 (0.39) | KCNH2MTNR1AMTNR1BCTSKCYP3A4 | |
| Hydrochloric Acid SCHEMBL27471182 | 0.94 | MTNR1A (0.35) | KCNH2MTNR1AMTNR1BCTSKPPARA | |
| SCHEMBL4610821 | 0.88 | EPHX2 (0.41) | — | |
| SCHEMBL19276531 | 0.80 | HRH1 (0.38) | MTNR1AMTNR1BCYP3A4 | |
| SCHEMBL2091960 | 0.78 | MTNR1A (0.40) | MTNR1AMTNR1BALDH1A1KDM4EMAPT | |
| SCHEMBL2095686 | 0.78 | MTNR1A (0.40) | MTNR1AMTNR1BALDH1A1KDM4EMAPT | |
| SCHEMBL2090144 | 0.77 | CES1 (0.37) | MTNR1AMTNR1BTBXAS1MAPT | |
| SCHEMBL2090142 | 0.77 | CES1 (0.37) | MTNR1AMTNR1BMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109096220-B | 2-carbonyl-5-aryl-1, 3, 4-oxadiazole steric hindrance type luminescent material and preparation method thereof | 信阳师范学院 | 2020-08-28 | — | — | CN | claimed |
| CN-106866649-A | The preparation method and application of the pyrazol acid amide compounds containing the oxadiazole structure of 5 aryl 1,3,4 | 南通大学 | 2017-06-20 | — | — | CN | claimed |
| CN-109096220-B | 2-carbonyl-5-aryl-1, 3, 4-oxadiazole steric hindrance type luminescent material and preparation method thereof | 信阳师范学院 | 2020-08-28 | — | — | CN | disclosed |
| CN-109096220-B | 2-carbonyl-5-aryl-1, 3, 4-oxadiazole steric hindrance type luminescent material and preparation method thereof | 信阳师范学院 | 2020-08-28 | — | — | CN | disclosed |
| CN-109844574-A | functional film | 大金工业株式会社 | 2019-06-04 | — | — | CN | disclosed |
| CN-109311191-A | The manufacturing method of transferred object with transfer pattern | 大金工业株式会社 | 2019-02-05 | — | — | CN | disclosed |
| CN-106866649-A | The preparation method and application of the pyrazol acid amide compounds containing the oxadiazole structure of 5 aryl 1,3,4 | 南通大学 | 2017-06-20 | — | — | CN | disclosed |
| US-7943645-B2 | Piperidine compounds for use as orexin receptor antagonist | SMITHKLINE BEECHAM LIMITED (GB) | 2011-05-17 | — | — | US | disclosed |
| US-20090082390-A1 | PIPERIDINE COMPOUNDS FOR USE AS OREXIN RECEPTOR ANTAGONIST | SMITHKLINE BEECHAM P.L.C. | 2009-03-26 | — | — | US | disclosed |
| US-20080280836-A1 | Anti-hypercholesterolemic biaryl azetidinone compounds | MORRIELLO GREGORI J | 2008-11-13 | — | — | US | disclosed |
| US-7423052-B2 | Piperidine compounds for use as orexin receptor antagoinst | SMITHKLINE BEECHAM P.L.C. (GB) | 2008-09-09 | — | — | US | disclosed |
| EP-1406897-B1 | COMPOUNDS | SMITHKLINE BEECHAM PLC (GB) | 2007-03-14 | — | — | EP | disclosed |
| US-20040215014-A1 | Piperidine compounds for use as orexin receptor antagonist | SMITHKLINE BEECHAM LIMITED (GB) | 2004-10-28 | — | — | US | disclosed |
| EP-1406897-A2 | COMPOUNDS | SmithKline Beecham plc (GB) | 2004-04-14 | — | — | EP | disclosed |
| WO-2003002559-A2 | PIPERIDINE COMPOUNDS FOR USE AS OREXIN RECEPTOR ANTAGONIST | SMITHKLINE BEECHAM P.L.C. (GB) | 2003-01-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080280836-A1 | Anti-hypercholesterolemic biaryl azetidinone compounds | APOB, PCSK9, CYP46A1 | KCNH2 500/4885MTNR1A 3744/4885MTNR1B 3167/4885 |
| US-20090082390-A1 | PIPERIDINE COMPOUNDS FOR USE AS OREXIN RECEPTOR ANTAGONIST | HCRTR2, HCRTR1, OXTR | KCNH2 827/4885MTNR1A 113/4885MTNR1B 95/4885 |
| US-20040215014-A1 | Piperidine compounds for use as orexin receptor antagonist | HCRTR2, HCRTR1, OXTR | KCNH2 948/4885MTNR1A 98/4885MTNR1B 85/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.