Phosphoric Acid

Phosphoric Acid

SCHEMBL21144485

CC=Cc1ccccc1Oc1ccccc1C=CC.O=P(O)(O)O

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.45
SRC P12931 2/20 0.44
KMT2A Q03164 3/20 0.43
MEN1 O00255 1/20 0.43
NFE2L2 Q16236 3/20 0.43
TFEB P19484 1/20 0.43
GAA P10253 2/20 0.43
KDM4E B2RXH2 2/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
MAPT P10636 3/20 0.40
PLA2G1B P04054 1/20 0.40
ATG4B Q9Y4P1 1/20 0.40
ATM Q13315 2/20 0.39
LMNA P02545 3/20 0.39
NPC1 O15118 2/20 0.39
RAB9A P51151 2/20 0.39
TLR4 O00206 1/20 0.39
TLR2 O60603 1/20 0.39
BCHE P06276 1/20 0.39
ALDH1A1 P00352 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3669785 0.88 NFE2L2 (0.45) HTTKMT2AMEN1NFE2L2TFEB
SCHEMBL21110871 0.88 NFE2L2 (0.45) HTTKMT2AMEN1NFE2L2TFEB
Sulfuric Acid SCHEMBL21110870 0.85 HTT (0.45) HTTKMT2AMEN1NFE2L2TFEB
SCHEMBL13158806 0.84 SRC (0.66) SRCKMT2AMEN1NFE2L2TFEB
Sulfuric Acid SCHEMBL3667450 0.84 HTT (0.44) HTTKMT2AMEN1NFE2L2TFEB
SCHEMBL3672332 0.84 HTT (0.44) HTTKMT2AMEN1NFE2L2TFEB
SCHEMBL16116225 0.81 HTT (0.45) HTTKMT2AMEN1NFE2L2TFEB
Phosphoric Acid SCHEMBL22721325 0.80 NFE2L2 (0.58) HTTSRCKMT2ANFE2L2GAA
SCHEMBL7210051 0.79 SRC (0.46) HTTSRCKMT2AMEN1NFE2L2
SCHEMBL7210055 0.79 SRC (0.46) HTTSRCKMT2AMEN1NFE2L2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11578028-B2 Surfactant composition DAI-ICHI KOGYO SEIYAKU CO., LTD. (JP) 2023-02-14 US claimed
WO-2021198866-A1 BLUE CATHODIC ELECTRODEPOSITION (CED) COATING COMPOSITION KANSAI NEROLAC PAINTS LIMITED (IN) 2021-10-07 WO claimed
EP-3508269-B1 SURFACTANT COMPOSITION DAI ICHI KOGYO SEIYAKU CO LTD (JP) 2021-06-23 EP claimed
US-20200331830-A1 SURFACTANT COMPOSITION DAI-ICHI KOGYO SEIYAKU CO., LTD. (JP) 2020-10-22 US claimed
US-20190217265-A1 SURFACTANT COMPOSITION DAI-ICHI KOGYO SEIYAKU CO., LTD. (JP) 2019-07-18 US claimed
CN-115698099-A Aqueous dispersion, coating agent for metal, and coating film 第一工业制药株式会社 2023-02-03 CN disclosed
CN-111253515-B Aqueous dispersion 第一工业制药株式会社 2022-11-25 CN disclosed
CN-111253522-B Aqueous dispersion 第一工业制药株式会社 2022-10-14 CN disclosed
WO-2021198866-A1 BLUE CATHODIC ELECTRODEPOSITION (CED) COATING COMPOSITION KANSAI NEROLAC PAINTS LIMITED (IN) 2021-10-07 WO disclosed
CN-111253522-A Aqueous dispersion 第一工业制药株式会社 2020-06-09 CN disclosed
CN-111253515-A Aqueous dispersion 第一工业制药株式会社 2020-06-09 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11578028-B2 Surfactant composition CHRM1, DEGS1, ASH2L HTT 2646/4885SRC 3879/4885KMT2A 866/4885
US-20200331830-A1 SURFACTANT COMPOSITION CHRM1, DEGS1, ASH2L HTT 2646/4885SRC 3879/4885KMT2A 866/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.