Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 known ✓ | O00206 | 1/20 | 0.38 |
| ▸ | LY96 known ✓ | Q9Y6Y9 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.42 |
| ▸ | TFEB | P19484 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | TLR2 | O60603 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3669785 | 0.87 | NFE2L2 (0.45) | HTTKMT2AMEN1NFE2L2TFEB | |
| SCHEMBL21110871 | 0.87 | NFE2L2 (0.45) | HTTKMT2AMEN1NFE2L2TFEB | |
| Phosphoric Acid SCHEMBL21144485 | 0.84 | HTT (0.45) | HTTKMT2AMEN1NFE2L2TFEB | |
| Sulfuric Acid SCHEMBL21110870 | 0.84 | HTT (0.45) | HTTKMT2AMEN1NFE2L2TFEB | |
| Sulfuric Acid SCHEMBL3667450 | 0.82 | HTT (0.44) | HTTKMT2AMEN1NFE2L2TFEB | |
| SCHEMBL16116225 | 0.79 | HTT (0.45) | HTTKMT2AMEN1NFE2L2TFEB | |
| SCHEMBL7896151 | 0.76 | LMNA (0.47) | HTTKMT2AMEN1NFE2L2TFEB | |
| SCHEMBL7896154 | 0.76 | LMNA (0.47) | HTTKMT2AMEN1NFE2L2TFEB | |
| SCHEMBL23037148 | 0.76 | LMNA (0.53) | HTTKMT2ANFE2L2GAASMN1; SMN2 | |
| SCHEMBL23037147 | 0.76 | LMNA (0.53) | HTTKMT2ANFE2L2GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1699828-B1 | POLYMER LATEX HAVING EXCELLENT IMPACT-RESISTANCE AND POWDER FLOW PROPERTY AND METHOD FOR PREPARING THE SAME | LG CHEMICAL LTD (KR) | 2010-03-24 | — | — | EP | claimed |
| US-20050203247-A1 | Polymer latex having excellent impact-resistance and powder flow property and method for preparing the same | LG CHEM, LTD. (KR) | 2005-09-15 | — | — | US | claimed |
| EP-1699828-B1 | POLYMER LATEX HAVING EXCELLENT IMPACT-RESISTANCE AND POWDER FLOW PROPERTY AND METHOD FOR PREPARING THE SAME | LG CHEMICAL LTD (KR) | 2010-03-24 | — | — | EP | disclosed |
| US-20050203247-A1 | Polymer latex having excellent impact-resistance and powder flow property and method for preparing the same | LG CHEM, LTD. (KR) | 2005-09-15 | — | — | US | disclosed |