Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 11/20 | 0.34 |
| ▸ | JAK1 | P23458 | 2/20 | 0.32 |
| ▸ | KDM5A | P29375 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14208073 | 0.75 | — | — | |
| SCHEMBL16249769 | 0.75 | — | — | |
| SCHEMBL14752927 | 0.73 | — | — | |
| SCHEMBL21145990 | 0.73 | CHRNB2 (0.42) | TSHR | |
| SCHEMBL23475238 | 0.72 | LMNA (0.43) | — | |
| SCHEMBL21146011 | 0.72 | LMNA (0.43) | — | |
| SCHEMBL21145980 | 0.72 | LMNA (0.43) | — | |
| SCHEMBL23475240 | 0.72 | LMNA (0.43) | — | |
| SCHEMBL21145993 | 0.72 | LMNA (0.43) | — | |
| SCHEMBL23475169 | 0.71 | BTK (0.50) | JAK1JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019118358-A1 | HEPATITIS B CAPSID ASSEMBLY MODULATORS | VenatoRx Pharmaceuticals, Inc. (US) | 2019-06-20 | — | — | WO | disclosed |