SCHEMBL21148474

SCHEMBL21148474

c1ccc(-c2nc(-c3ccc4c5ccccc5c5ccccc5c4c3)nc(-c3cccc4oc5ccccc5c34)n2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.38
ALDH1A1 P00352 5/20 0.38
HPGD P15428 5/20 0.38
TSHR P16473 3/20 0.38
KDM4E B2RXH2 3/20 0.38
SMN1; SMN2 Q16637 3/20 0.38
ATM Q13315 2/20 0.38
TP53 P04637 2/20 0.38
NFKB1 P19838 1/20 0.38
MAPK1 P28482 1/20 0.38
NFKB2 Q00653 1/20 0.38
RELA Q04206 1/20 0.38
HSD17B10 Q99714 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
PLA2G2A P14555 2/20 0.37
PLA2G4A P47712 2/20 0.37
PLA2G10 O15496 1/20 0.37
MEN1 O00255 4/20 0.36
KMT2A Q03164 4/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21148472 0.99 PLA2G2A (0.38) MAPTALDH1A1HPGDTSHRKDM4E
SCHEMBL25557515 0.97 PLA2G2A (0.41) MAPTALDH1A1HPGDTSHRKDM4E
SCHEMBL27321270 0.97 ALDH1A1 (0.37) MAPTALDH1A1HPGDTSHRKDM4E
SCHEMBL22876471 0.96 PLA2G2A (0.40) MAPTALDH1A1HPGDTSHRKDM4E
SCHEMBL19802321 0.96 ALOX5 (0.36) MAPTALDH1A1HPGDTSHRKDM4E
SCHEMBL24216460 0.96 HCRTR1 (0.38) MAPTALDH1A1HPGDTSHRKDM4E
SCHEMBL24217166 0.96 PLA2G2A (0.40) MAPTALDH1A1HPGDTSHRKDM4E
SCHEMBL26048288 0.96 ALOX5 (0.38) MAPTALDH1A1HPGDKDM4ESMN1; SMN2
SCHEMBL24215910 0.95 HCRTR1 (0.38) MAPTALDH1A1HPGDTSHRKDM4E
SCHEMBL24216957 0.95 PLA2G2A (0.37) MAPTALDH1A1HPGDTSHRKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230329097-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE SAMSUNG SDI CO LTD (KR) 2023-10-12 US disclosed
US-20230329097-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE SAMSUNG SDI CO LTD (KR) 2023-10-12 US disclosed
WO-2023153905-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DIODE, ORGANIC OPTOELECTRONIC DIODE, AND DISPLAY DEVICE 삼성에스디아이 주식회사 2023-08-17 WO disclosed
US-20190214573-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2019-07-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190214573-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE OR10J3, OCIAD2, OCIAD1 MAPT 1761/4885ALDH1A1 191/4885HPGD 1901/4885
US-20230329097-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE OR10J3, OCIAD2, OCIAD1 MAPT 1761/4885ALDH1A1 191/4885HPGD 1901/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.