Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | GSK3A | P49840 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | IGF1R | P08069 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21157986 | 0.91 | RAB9A (0.48) | ALDH1A1POLBCALM1MAPTSMN1; SMN2 | |
| SCHEMBL22190370 | 0.83 | ATM (0.47) | ALDH1A1POLBMAPTHTR2CHTR2B | |
| SCHEMBL22554349 | 0.83 | ALDH1A1 (0.54) | ALDH1A1POLBMAPTSMN1; SMN2ALOX15 | |
| SCHEMBL21149335 | 0.80 | SIRT2 (0.38) | ALDH1A1POLBSMN1; SMN2TAAR1SIRT2 | |
| SCHEMBL22190338 | 0.80 | ALDH1A1 (0.47) | ALDH1A1POLBMAPTHTR2BTAAR1 | |
| SCHEMBL21148547 | 0.80 | SIRT2 (0.37) | ALDH1A1POLBTAAR1SIRT2 | |
| SCHEMBL22190335 | 0.80 | ALDH1A1 (0.35) | ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL21121188 | 0.80 | RAB9A (0.46) | ALDH1A1SMN1; SMN2GSK3AGSK3B | |
| SCHEMBL22190357 | 0.79 | KCNH2 (0.43) | ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL22190361 | 0.76 | ATM (0.42) | ALDH1A1MAPTSMN1; SMN2GSK3AGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11998901-B2 | Metal complex, method for producing same, and method for producing gamma-lactam compound using same | INSTITUTE FOR BASIC SCIENCE (KR) | 2024-06-04 | — | — | US | disclosed |
| CN-111566116-B | Novel metal complex, process for producing the same, and process for producing gamma-lactam compound using the same | 基础科学研究院 | 2023-06-09 | — | — | CN | disclosed |
| US-20220168717-A1 | NOVEL METAL COMPLEX, METHOD FOR PRODUCING SAME, AND METHOD FOR PRODUCING GAMMA-LACTAM COMPOUND USING SAME | INSTITUTE FOR BASIC SCIENCE (KR) | 2022-06-02 | — | — | US | disclosed |
| US-20220168717-A1 | NOVEL METAL COMPLEX, METHOD FOR PRODUCING SAME, AND METHOD FOR PRODUCING GAMMA-LACTAM COMPOUND USING SAME | INSTITUTE FOR BASIC SCIENCE (KR) | 2022-06-02 | — | — | US | disclosed |
| US-11344872-B2 | Metal complex, method for producing same, and method for producing gamma-lactam compound using same | INSTITUTE FOR BASIC SCIENCE (KR) | 2022-05-31 | — | — | US | disclosed |
| US-11344872-B2 | Metal complex, method for producing same, and method for producing gamma-lactam compound using same | INSTITUTE FOR BASIC SCIENCE (KR) | 2022-05-31 | — | — | US | disclosed |
| CN-111170918-B | Method for synthesizing gamma-lactam and delta-lactam through C-H amine | 山东大学 | 2021-09-21 | — | — | CN | disclosed |
| US-20200330969-A1 | NOVEL METAL COMPLEX, METHOD FOR PRODUCING SAME, AND METHOD FOR PRODUCING GAMMA-LACTAM COMPOUND USING SAME | KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2020-10-22 | — | — | US | disclosed |
| US-20200330969-A1 | NOVEL METAL COMPLEX, METHOD FOR PRODUCING SAME, AND METHOD FOR PRODUCING GAMMA-LACTAM COMPOUND USING SAME | KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2020-10-22 | — | — | US | disclosed |
| CN-111566116-A | Novel metal complex, method for producing same, and method for producing gamma-lactam compound using same | 基础科学研究院 | 2020-08-21 | — | — | CN | disclosed |
| CN-111170918-A | Method for synthesizing gamma-lactam and delta-lactam through C-H amine | 山东大学 | 2020-05-19 | — | — | CN | disclosed |
| WO-2019135600-A1 | NOVEL METAL COMPLEX, METHOD FOR PRODUCING SAME, AND METHOD FOR PRODUCING GAMMA-LACTAM COMPOUND USING SAME | 기초과학연구원 | 2019-07-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220168717-A1 | NOVEL METAL COMPLEX, METHOD FOR PRODUCING SAME, AND METHOD FOR PRODUCING GAMMA-LACTAM COMPOUND USING SAME | COASY, NOTUM, MRPL21 | ALDH1A1 2634/4885POLB 1168/4885CALM1 1780/4885 |
| US-11344872-B2 | Metal complex, method for producing same, and method for producing gamma-lactam compound using same | COASY, NOTUM, MRPL21 | ALDH1A1 2316/4885POLB 1090/4885CALM1 2025/4885 |
| US-11998901-B2 | Metal complex, method for producing same, and method for producing gamma-lactam compound using same | COASY, NOTUM, MRPL21 | ALDH1A1 2316/4885POLB 1090/4885CALM1 2025/4885 |
| US-20200330969-A1 | NOVEL METAL COMPLEX, METHOD FOR PRODUCING SAME, AND METHOD FOR PRODUCING GAMMA-LACTAM COMPOUND USING SAME | COASY, NOTUM, MRPL21 | ALDH1A1 2634/4885POLB 1168/4885CALM1 1780/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.