Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.31 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22190370 | 0.84 | ATM (0.47) | ALDH1A1POLBATMTDP1L3MBTL1 | |
| SCHEMBL22190338 | 0.84 | ALDH1A1 (0.47) | ALDH1A1POLB | |
| SCHEMBL21148547 | 0.84 | SIRT2 (0.37) | ALDH1A1POLBL3MBTL1 | |
| SCHEMBL21149335 | 0.84 | SIRT2 (0.38) | ALDH1A1POLBATMTDP1L3MBTL1 | |
| SCHEMBL21121188 | 0.83 | RAB9A (0.46) | ALDH1A1ATMTDP1L3MBTL1NPC1 | |
| SCHEMBL21148530 | 0.80 | ALDH1A1 (0.57) | ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL22190353 | 0.80 | HTR2B (0.43) | — | |
| SCHEMBL22190357 | 0.80 | KCNH2 (0.43) | ALDH1A1POLBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL22190361 | 0.80 | ATM (0.42) | ALDH1A1ATMTDP1L3MBTL1NPC1 | |
| SCHEMBL22190354 | 0.79 | MAPT (0.43) | ALDH1A1ATMTDP1L3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020141734-A1 | METHOD FOR PREPARING CHIRAL GAMMA-LACTAM COMPOUND AND METAL COMPLEX THEREFOR | 기초과학연구원 | 2020-07-09 | — | — | WO | disclosed |
| WO-2020141734-A1 | METHOD FOR PREPARING CHIRAL GAMMA-LACTAM COMPOUND AND METAL COMPLEX THEREFOR | 기초과학연구원 | 2020-07-09 | — | — | WO | disclosed |