Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21149844 | 0.85 | HDAC1 (0.58) | LMNAFFAR1HDAC1HDAC3MAPK1 | |
| SCHEMBL22201229 | 0.84 | PLAAT3 (0.47) | FFAR1HDAC1HDAC3MAPK1ADRA1A | |
| SCHEMBL22201167 | 0.84 | HDAC3 (0.47) | FFAR1HDAC1HDAC3MAPK1ADRA1A | |
| SCHEMBL21149328 | 0.84 | PLAAT3 (0.47) | FFAR1HDAC1HDAC3MAPK1ADRA1A | |
| SCHEMBL22201204 | 0.83 | HDAC1 (0.48) | FFAR1HDAC1HDAC8TAAR1PLAAT3 | |
| SCHEMBL21148532 | 0.81 | ALOX5 (0.57) | FFAR1PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL22201278 | 0.80 | MAPT (0.58) | FFAR1HDAC1HDAC3MAPK1ADRA1A | |
| SCHEMBL21148799 | 0.79 | TSHR (0.49) | SMN1; SMN2NPC1RAB9A | |
| SCHEMBL22201127 | 0.79 | MAPT (0.61) | HDAC1HDAC3MAPK1ADRA1AHDAC4 | |
| SCHEMBL655425 | 0.77 | SMN1; SMN2 (0.67) | LMNAFFAR1HDAC1HDAC3MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020141734-A1 | METHOD FOR PREPARING CHIRAL GAMMA-LACTAM COMPOUND AND METAL COMPLEX THEREFOR | 기초과학연구원 | 2020-07-09 | — | — | WO | disclosed |
| WO-2019135600-A1 | NOVEL METAL COMPLEX, METHOD FOR PRODUCING SAME, AND METHOD FOR PRODUCING GAMMA-LACTAM COMPOUND USING SAME | 기초과학연구원 | 2019-07-11 | — | — | WO | disclosed |