Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.52 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.52 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.52 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.51 |
| ▸ | FAAH | O00519 | 3/20 | 0.50 |
| ▸ | CES1 | P23141 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22201127 | 0.98 | MAPT (0.61) | MAPTRXFP1HDAC1HDAC2HDAC3 | |
| SCHEMBL21149844 | 0.95 | HDAC1 (0.58) | MAPTRXFP1HDAC1HDAC2HDAC3 | |
| SCHEMBL22201229 | 0.80 | PLAAT3 (0.47) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL21148548 | 0.80 | LMNA (0.49) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL22201167 | 0.80 | HDAC3 (0.47) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL21149328 | 0.80 | PLAAT3 (0.47) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL22201222 | 0.79 | CYP1A2 (0.66) | HDAC1HDAC2HDAC3HDAC8HDAC6 | |
| SCHEMBL22201233 | 0.79 | TAAR1 (0.46) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL8790943 | 0.78 | MAPT (0.66) | MAPTRXFP1HDAC1HDAC2HDAC3 | |
| SCHEMBL21148532 | 0.78 | ALOX5 (0.57) | ALOX5PLAAT3PLAAT5PLAAT2PLAAT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020141734-A1 | METHOD FOR PREPARING CHIRAL GAMMA-LACTAM COMPOUND AND METAL COMPLEX THEREFOR | 기초과학연구원 | 2020-07-09 | — | — | WO | disclosed |