SCHEMBL21148741

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21149216	0.94	ALOX5 (0.37)	HDAC8HDAC6CA12CA1CA2
	SCHEMBL21149238	0.94	ALOX5 (0.37)	F9ALOX5ALDH1A1MAPTHPGD
	SCHEMBL21148613	0.92	GPR3 (0.40)	F9ALOX5KDM4EALDH1A1MAPT
	SCHEMBL25730550	0.91	ALOX5 (0.37)	F9ALOX5KDM4EALDH1A1MAPT
	SCHEMBL21149233	0.90	PIM3 (0.39)	F9ALOX5KDM4EALDH1A1MAPT
	SCHEMBL27361242	0.90	TSHR (0.43)	HDAC8HDAC6CA12CA1CA2
	SCHEMBL21149237	0.89	S1PR5 (0.38)	ALOX5SMN1; SMN2GPR3CYP1A2BRDT
	SCHEMBL21148233	0.89	TSHR (0.43)	HDAC8HDAC6CA12CA1CA2
	SCHEMBL22329592	0.89	ALOX5 (0.37)	F9ALOX5KDM4EALDH1A1MAPT
	SCHEMBL19501982	0.89	ALOX5 (0.37)	F9ALOX5KDM4EALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.